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          • Primary Antibodies ›
          • NXN Antibodies

          Proteintech

          NXN Monoclonal Antibody (2C6A4), CoraLite® Plus 488

          View all (11) NXN antibodies
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          Cite NXN Monoclonal Antibody (2C6A4), CoraLite® Plus 488

          • Antibody Testing Data (1)
          NXN Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          NXN Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          NXN Antibody (CL488-66603) in ICC/IF

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          NXN Antibody in Immunocytochemistry (ICC/IF)

          Product Details

          CL488-66603

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          -

          Flow Cytometry (Flow)

          0.4 µg/1x10^6 cell suspension
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          2C6A4

          Immunogen

          Recombinant protein
          View immunogen

          Conjugate

          CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488
          • Unconjugated
          • CoraLite 594
          • Request custom conjugation

          Excitation/Emission Max

          493/522 nm

          Form

          Liquid

          Purification

          Protein G

          Storage buffer

          PBS with 50% glycerol, 0.5% BSA

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: ADVSLHRNPA TLKLWNKYRI SNIPSLIFLD ATTGKVVCRN GLLVIRDDPE GLEFPWGPKP FREVIAGPLL RNNGQSLESS SLEGSHVGVY FSAHWCPPCR SLTRVLVESY RKIKEAGQNF EIIFVSADRS EESFKQYFSE MPWLAVPYTD EARRSRLNRL YGIQGIPTLI MLDPQGEVIT RQGRVEVLND EDCREFPWHP KPVLELSDSN AAQLNEGPCL VLFVDSEDDG ESEAAKQLIQ PIAEKIIAKY KAKEEEAPLL FFVAGEDDMT DSLRDYTNLP EAAPLLTILD MSARAKYVMD VEEITPAIVE AFVNDFLAEK LKPEPI

          Target Information

          This gene encodes a member of the thioredoxin superfamily, a group of small, multifunctional redox-active proteins. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. The encoded protein acts a redox-dependent regulator of the Wnt signaling pathway and is involved in cell growth and differentiation.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Nucleoredoxin; nucleoredoxin 1; Protein Red-1

          View more View less

          Gene Aliases: Gn25; l11Jus13; NRX; NXN; TRG-4

          View more View less

          UniProt ID: (Human) Q6DKJ4, (Mouse) P97346

          View more View less

          Entrez Gene ID: (Human) 64359, (Mouse) 18230, (Rat) 360577

          View more View less

          Function(s)
          thioredoxin-disulfide reductase activity protein-disulfide reductase activity protein binding oxidoreductase activity
          Process(es)
          Wnt signaling pathway cell differentiation negative regulation of Wnt signaling pathway negative regulation of protein ubiquitination cell redox homeostasis oxidation-reduction process cardiovascular system development cellular oxidant detoxification multicellular organism development
          It has to be done as per old AB suggested Products section.
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