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Immunogen sequence: PFEDDLRRDL GRQFSVERLP AVVVLKPDGD VLTRDGADEI QRLGTACFAN WQEAAEVLDR NFQLPEDLED QEPRSLTECL RRHKYRVE
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 76%.
Retinitis pigmentosa (RP) is a disease that leads to blindness by degeneration of cone photoreceptors. Rods produce factors required for cone viability. The protein encoded by this gene is one of those factors and is similar to a truncated form of thioredoxin. This gene has been proposed to have therapeutic value against RP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Nucleoredoxin-like protein 1; rod-derived cone viability factor; thioredoxin-like 6; Thioredoxin-like protein 6
Gene Aliases: NXNL1; RDCVF; TXNL6
UniProt ID: (Human) Q96CM4
Entrez Gene ID: (Human) 115861
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