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Invitrogen
NY-BR-1 Monoclonal Antibody (NY-BR-1 No. 2)
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Product Details
MA5-12645
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
NY-BR-1 No. 2
Immunogen
A 77 aa peptide from human NYBR-1 protein
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10977217
Product Specific Information
MA5-12645 targets NY-BR-1 in IHC (P, F) applications and shows reactivity with Human samples.
The MA5-12645 immunogen is a 77 aa peptide from human NYBR-1 protein.
Target Information
NY-BR-1 is a novel differentiation marker predominantly expressed in normal breast and breast cancer. It has been shown by Immunohistochemistry (IHC) that NY-BR-1 was present solely in ductal epithelium of normal breast tissue. Invasive carcinoma of the breast and carcinoma in situ were positive for NY-BR-1, whereas most other tumors and normal tissues are negative, with the exceptions of one-third of sweat gland carcinomas and around two percent of prostate carcinoma. NY-BR-1 is reported to express more frequently in estrogen-positive and lymph node-negative primary carcinomas, and more commonly in grade 1 than in grade 2 or grade 3. In a study by Varga et al (2006) forty-nine percent of lymph node metastasis were shown to be positive.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ankyrin repeat domain-containing protein 30A; breast cancer antigen NY-BR-1; Serologically defined breast cancer antigen NY-BR-1
Gene Aliases: ANKRD30A; NY-BR-1
UniProt ID: (Human) Q9BXX3
Entrez Gene ID: (Human) 91074
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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