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Invitrogen
Naked2 Polyclonal Antibody
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FIGURE: 1 / 4
Naked2 Antibody (PA5-48336) in ICC/IF
Immunocytochemistry analysis of Naked2 in A375 cells. Samples were incubated in Naked2 polyclonal antibody (Product # PA5-48336) followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
Product Details
PA5-48336
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 366-393 amino acids from the C-terminal region of human NKD2.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2633794
Target Information
Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dvl-binding protein NKD2; hNkd2; naked cuticle-2; Naked-2; Protein naked cuticle homolog 2
Gene Aliases: Naked2; NKD2
UniProt ID: (Human) Q969F2
Entrez Gene ID: (Human) 85409
exocytosis
positive regulation of protein processing
Wnt signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Golgi vesicle fusion to target membrane
protein targeting to plasma membrane
positive regulation of establishment of protein localization to plasma membrane
negative regulation of canonical Wnt signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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