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Nebulette encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Actin-binding Z-disk protein; LIM and SH3 protein 2; LIM zinc-binding domain-containing Nebulette; LIM-nebulette; Nebulette
Gene Aliases: 1200007O21Rik; A630080F05Rik; BB140644; C10orf113; D830029A09Rik; LASP2; LNEBL; NEBL
UniProt ID: (Human) O76041, (Mouse) Q9DC07
Entrez Gene ID: (Human) 10529, (Rat) 307189, (Mouse) 74103
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