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This antibody reacts with Orf1 (FrpD), a 28 - 32 kDa Neisseria meningitidis outer membrane lipoprotein. Orf1 is highly conserved in a set of meningococcal strains representative of all serogroups and does not exhibit any similarity to known sequences of other organisms.
Western Blot: Reducing conditions.
The genus Neisseria contains a number of species which are normal flora and pathogens of humans and animals. Of these species, the species of human origin, and particularly the pathogenic species, N. gonorrhoeae and N. meningitidis, have been studied extensively in an effort to control the infections they cause. Gonorrhea, caused by N. gonorrhoeae, is one of the most frequently reported infectious diseases in the United States and worldwide. Of the Neisseria and related species, only N. gonorrhoeae is considered always to be pathogenic i.e., cause disease. N. gonorrhoeae is not considered to be normal flora under any circumstances.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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