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This target displays homology in the following species: Mouse: 100%
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HsT17534; NEO; Neogenin; NGNDKFZp547A066
Gene Aliases: 2610028H22Rik; AI327052; D930014N22Rik; Igdcc2; Neo1; Ngn
UniProt ID: (Mouse) P97798
Entrez Gene ID: (Mouse) 18007
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