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Invitrogen
Neuropilin 2 Polyclonal Antibody
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FIGURE: 1 / 2
Neuropilin 2 Antibody (PA5-75451) in WB
Western blot analysis of Neuropilin 2 in Lane 1: PC3 whole cell lysate (40 µg), Lane 2: HEK293T whole cell lysate (20 µg), Lane 3: A549 whole cell lysate (20 µg), Lane 4: PC12 whole cell lysate (40 µg), Lane 5: the Kidney tissue lysate of mouse (40 µg). Samples were incubated with Neuropilin 2 polyclonal antibody (Product # PA5-75451) at a dilution of 1:500.
Product Details
PA5-75451
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 341-390 of Human Neuropilin 2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2719179
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C) and SEMA3F protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F), and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Neuropilin-2; neuropilin-2a(17); neuropilin-2a(22); neuropilin-2b(0); receptor for VEGF165 and semaphorins class3; Vascular endothelial cell growth factor 165 receptor 2
Gene Aliases: 1110048P06Rik; Np-2; NP2; Npn-2; NPN2; NRP2; PRO2714; VEGF165R2
UniProt ID: (Human) O60462, (Mouse) O35375, (Rat) O35276
Entrez Gene ID: (Human) 8828, (Mouse) 18187, (Rat) 81527
angiogenesis
positive regulation of endothelial cell proliferation
cell adhesion
axon guidance
positive regulation of endothelial cell migration
nerve development
vascular endothelial growth factor signaling pathway
vascular endothelial growth factor receptor signaling pathway
axon extension involved in axon guidance
sympathetic ganglion development
sympathetic neuron projection extension
sympathetic neuron projection guidance
semaphorin-plexin signaling pathway involved in neuron projection guidance
neural crest cell migration
neuron migration
multicellular organism development
nervous system development
heart development
facial nerve structural organization
vestibulocochlear nerve structural organization
gonadotrophin-releasing hormone neuronal migration to the hypothalamus
cell differentiation
ventral trunk neural crest cell migration
negative chemotaxis
trigeminal ganglion development
ganglion morphogenesis
semaphorin-plexin signaling pathway
sensory neuron axon guidance
neural crest cell migration involved in autonomic nervous system development
facioacoustic ganglion development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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