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Neuroplastin Antibody (PA5-96882) in WB
Western blot analysis of Neuroplastin in extracts of various cell lines. Samples were incubated with Neuroplastin Polyclonal antibody (Product # PA5-96882) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-96882
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 29-200 of human NPTN (NP_0594291)
Conjugate
Form
Liquid
Concentration
1.79 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2808684
Product Specific Information
Immunogen sequence: QNEPRIVTSE EVIIRDSPVL PVTLQCNLTS SSHTLTYSYW TKNGVELSAT RKNASNMEYR INKPRAEDSG EYHCVYHFVS APKANATIEV KAAPDITGHK RSENKNEGQD ATMYCKSVGY PHPDWIWRKK ENGMPMDIVN TSGRFFIINK ENYTELNIVN LQITEDPGEY EC; Positive Samples: SKOV3, Jurkat; Cellular Location: Cell membrane, Single-pass type I membrane protein
Target Information
This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glycoprotein 55; Glycoprotein 55/65; glycoprotein 65; gp55/65; Neuroplastin; SDR-1; stromal cell derived factor receptor 1; Stromal cell-derived receptor 1
Gene Aliases: AW554172; GP55; GP65; np55; np65; NPTN; SDFR1; SDR-1; SDR1
UniProt ID: (Human) Q9Y639, (Mouse) P97300, (Rat) P97546
Entrez Gene ID: (Human) 27020, (Mouse) 20320, (Rat) 56064
positive regulation of protein phosphorylation
homophilic cell adhesion via plasma membrane adhesion molecules
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of cytosolic calcium ion concentration
visual learning
positive regulation of neuron projection development
peptidyl-tyrosine phosphorylation
positive regulation of fibroblast growth factor receptor signaling pathway
positive regulation of long-term neuronal synaptic plasticity
long-term synaptic potentiation
positive regulation of ERK1 and ERK2 cascade
positive regulation of long-term synaptic potentiation
positive regulation of cellular protein localization
cell adhesion
nervous system development
regulation of cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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