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Alomone Labs, LTD
Neurotrophin 4 (NT-4) Polyclonal Antibody
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Neurotrophin 4 (NT-4) Antibody (ANT-004-200UL) in IHC
Expression of Neurotrophin 4 in mouse spinal cord - Immunohistochemical staining of mouse spinal cord using Anti-Neurotrophin 4 (NT-4) Antibody (#ANT-004). The spinal ventral horn (VH) was very lightly stained. However, in the perimeterof the white matter (WM) there were NT-4 immunoreactive cells with a small soma (triangles) and some had a stained process (arrows).
Product Details
ANT-004-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LGEVPAAGGSPL(C), corresponding to amino acid residues 43-52 of mature human NT-4(residues 123-132 of the precursor NT-4), Intracellular
Conjugate
Form
Lyophilized
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 5% sucrose, 1% BSA
Contains
0.025% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: neurotrophic factor 4; neurotrophic factor 5; Neurotrophin 4/5; Neurotrophin 5 (neurotrophin 4/5); neurotrophin 5 (neurotrophin 4/5); Neurotrophin-4; Neurotrophin-5; Neutrophic factor 4; Neutrophic factor 5; NT-4; NT-5; NT4/NT5
Gene Aliases: 2900040K06Rik; AI462899; GLC10; GLC1O; NT-4; NT-4/5; NT-5; NT4; NT4/5; NT4P; NT5; Ntf-5; NTF4; NTF5
UniProt ID: (Human) P34130, (Rat) P34131, (Mouse) Q80VU4
Entrez Gene ID: (Human) 4909, (Rat) 25730, (Mouse) 78405
transmembrane receptor protein tyrosine kinase signaling pathway
cell-cell signaling
ganglion mother cell fate determination
long-term memory
sensory organ boundary specification
adult locomotory behavior
epidermis development
mechanoreceptor differentiation
negative regulation of neuron apoptotic process
regulation of neuron differentiation
neuron projection morphogenesis
innervation
taste bud development
regulation of synaptic plasticity
negative regulation of cell death
Performance Guarantee
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