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Invitrogen
Neurotrypsin Polyclonal Antibody
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Product Details
PA5-20363
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 23 amino acid peptide from near the amino terminus of human neurotrypsin.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11154817
Product Specific Information
A suggested positive control is SK-N-SH cell lysate.
PA5-20363 can be used with blocking peptide PEP-0483.
Target Information
Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain-specific serine protease 3; BSSP-3; Leydin; Motopsin; Neurotrypsin; peptidase, serine, 12 (neurotrypsin, motopsin); protease, serine, 12 (neurotrypsin, motopsin); protease, serine, 12 neurotrypsin (motopsin); Serine protease 12
Gene Aliases: BSSP-3; BSSP3; motopsin; MRT1; Nt; PRSS12
UniProt ID: (Human) P56730, (Rat) G3V801, (Mouse) O08762
Entrez Gene ID: (Human) 8492, (Rat) 85266, (Mouse) 19142
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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