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Alomone Labs, LTD
Nicotinic Acetylcholine Receptor alpha 9 (CHRNA9) Polyclonal Antibody
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FIGURE: 1 / 2
Nicotinic Acetylcholine Receptor alpha 9 (CHRNA9) Antibody (ANC-019-200UL) in IHC (F)
Expression of nAChR alpha 9 in rat DRG - Immunohistochemical staining of rat dorsal root ganglion (DRG) frozen sections using Anti-Nicotinic Acetylcholine Receptor alpha 9 (CHRNA9) Antibody (#ANC-019), (1:400), followed by goat- Anti-rabbit-AlexaFluor-488. nAChR alpha 9 staining (in green) appears in neuronal soma (arrows).DAPI is used as the counterstain (blue).
Product Details
ANC-019-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)KDHKATNSKGSEWKK, corresponding to amino acid residues 436-450 of rat nAChR alpha 9, 2ndintracellular loop
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
Target Information
CHRNA9 is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor superfamily. CHRNA9 is a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. It is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea.This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. The protein is additionally expressed in keratinocytes, the pituitary gland, B-cells and T-cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetylcholine receptor; acetylcholine receptor alpha 9 subunit (nAChR); acetylcholine receptor, neuronal nicotinic, alpha-9 subunit; cholinergic receptor; cholinergic receptor, nicotinic alpha 9; cholinergic receptor, nicotinic, alpha 9 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 9; NACHR alpha 9; NACHR alpha-9; neuronal acetylcholine receptor protein, alpha-9 subunit; Neuronal acetylcholine receptor subunit alpha-9; nicotinic acetylcholine receptor subunit alpha 9; Nicotinic acetylcholine receptor subunit alpha-9
Gene Aliases: 2410015I05Rik; Acra9; CHRNA9; EG666827; Gm8311; HSA243342; NACHRA9
UniProt ID: (Human) Q9UGM1, (Rat) P43144
Entrez Gene ID: (Human) 55584, (Mouse) 231252, (Rat) 65024
cation transport
positive regulation of cytosolic calcium ion concentration
inner ear morphogenesis
detection of mechanical stimulus involved in sensory perception of sound
cation transmembrane transport
signal transduction
synaptic transmission, cholinergic
calcium ion transmembrane transport
sensory perception of sound
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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