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Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
NOGO (RTN4R) is a receptor for RTN4, OMG, and MAG. Its signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. NOGO also mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS. In addition, NOGO acts with RTN4 and LINGO1 to regulate neuronal precursor cell motility during cortical development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HGNC:1860; NgR; NgR1; nogo 66 receptor; Nogo receptor; nogo receptor; Nogo-66 receptor; Nogo-66 receptor; Nogo66 receptor; Nogo66 receptor-1; OTTHUMP00000197866; Reticulon-4 receptor; UNQ330/PRO526
Gene Aliases: NGR; NgR1; NOGOR; RTN4R; UNQ330/PRO526
UniProt ID: (Human) Q9BZR6, (Rat) Q99M75, (Mouse) Q99PI8
Entrez Gene ID: (Human) 65078, (Rat) 113912, (Mouse) 65079
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