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Invitrogen
Nortriptyline Polyclonal Antibody
Product Details
PA1-75481
Product Specifications
Species Reactivity
Chemical
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Nortriptyline-BTG
Conjugate
Form
Liquid
Purification
purified
Storage buffer
PBS, pH 7.1
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1090564
Product Specific Information
Working Concentration: 5 µg/mL. Sensitivity: 10 ng/mL Nortriptyline produces 45% inhibition in a competitive ELISA employing Tricyclic Antidepressants (TCA) (4) polyclonal antibody.
Target Information
Nortriptyline Base is a tricyclic antidepressant agent used for short-term treatment of various forms of depression. Nortriptyline blocks the norepinephrine presynaptic receptors, thereby blocking the reuptake of this neurotransmitter and raising the concentration in the synaptic cleft in the CNS. Nortriptyline also binds to alpha-adrenergic, histaminergic and cholinergic receptors. Long-term treatment with nortriptyline produces a downregulation of adrenergic receptors due to the increased stimulation of these receptors. [National Center for Biotechnology Information. PubChem Compound Database; CID=4543].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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