Proteintech

OAT1 Polyclonal Antibody

OAT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 2

OAT1 Antibody (26574-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 26574-1-AP (OAT1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Product Image Gallery

Product Details

26574-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 9 publications 9 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SLC22A6 Fusion Protein Ag24234

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

333 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Aliquoting is unnecessary for -20°C storage.

Target Information

The protein is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Amelioration effects of α-viniferin on hyperuricemia and hyperuricemia-induced kidney injury in mice.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Guo XL,Gao YY,Yang YX,Zhu QF,Guan HY,He X,Zhang CL,Wang Y,Xu GB,Zou SH,Wei MC,Zhang J,Zhang JJ,Liao SG

Tue Jul 25 00:00:00 UTC 2023

Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.

Journal of ethnopharmacology

Zhang Y,Wang S,Dai X,Liu T,Liu Y,Shi H,Yin J,Xu T,Zhang Y,Zhao D,Sukhorukov V,Orekhov AN,Gao S,Wang L,Zhang D

Thu Aug 10 00:00:00 UTC 2023

Inhibition of Transforming Growth Factor-β Improves Primary Renal Tubule Cell Differentiation in Long-Term Culture.

Tissue engineering. Part A

Hunter K,Larsen JA,Love HD,Evans RC,Roy S,Zent R,Harris RC,Wilson MH,Fissell WH

Wed Feb 01 00:00:00 UTC 2023

Sanghuangporus vaninii ethanol extract alleviates hyperuricemic renal injury by regulating the uric acid transporters and inhibiting HK-2 apoptosis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Hua L,Zhang S,Yang J,Zhou X,Shi S

Tue Aug 01 00:00:00 UTC 2023

Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.

Pharmaceuticals (Basel, Switzerland)

Liu T,Gao H,Zhang Y,Wang S,Lu M,Dai X,Liu Y,Shi H,Xu T,Yin J,Gao S,Wang L,Zhang D

Mon Nov 21 00:00:00 UTC 2022

Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia.

Frontiers in pharmacology

Gao T,Xu J,Xiao Y,Li J,Hu W,Su X,Shen X,Yu W,Chen Z,Huang B,Li H,Wang X

Tue Sep 20 00:00:00 UTC 2022

Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.

Bioengineered

Zhao X,Wang J,Tang L,Li P,Ru J,Bai Y

Wed Dec 01 00:00:00 UTC 2021

Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway.

European journal of pharmacology

Lin G,Yu Q,Xu L,Huang Z,Mai L,Jiang L,Su Z,Xie J,Li Y,Liu Y,Lin Z,Chen J

Sun Dec 05 00:00:00 UTC 2021

Active components from Lagotis brachystachya maintain uric acid homeostasis by inhibiting renal TLR4-NLRP3 signaling in hyperuricemic mice.

Inflammopharmacology

Zhu JX,Yang HY,Hu WQ,Cheng J,Liu Y,Yi LT,Cheng HY

Sun Aug 01 00:00:00 UTC 2021

Bioinformatics

Protein Aliases: hOAT1; hPAHT; hROAT1; Kidney-specific transport protein; mNKT; mOAT1; mROAT1; Novel kidney transcript; Organic anion transporter 1; organic cationic transporter-like 1; PAH transporter; para-aminohippurate transporter; Renal organic anion transporter 1; solute carrier family 22 (organic anion transporter), member 6; Solute carrier family 22 member 6

View more View less

Gene Aliases: HOAT1; mOat1; NKT; OAT1; Orctl1; PAHT; ROAT1; SLC22A6

View more View less

UniProt ID: (Human) Q4U2R8, (Mouse) Q8VC69

View more View less

Entrez Gene ID: (Human) 9356, (Mouse) 18399

View more View less

Function(s)

inorganic anion exchanger activity protein binding organic anion transmembrane transporter activity anion:anion antiporter activity sodium-independent organic anion transmembrane transporter activity chloride ion binding protein homodimerization activity ion transmembrane transporter activity transmembrane transporter activity

Process(es)

anion transport organic anion transport alpha-ketoglutarate transport ion transmembrane transport sodium-independent organic anion transport protein homooligomerization transmembrane transport renal tubular secretion anion transmembrane transport inorganic anion transport response to methotrexate

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

OAT1 Polyclonal Antibody

OAT1 Antibody (26574-1-AP) in IHC (P)

Product Details

26574-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!