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Progen
OATP2/OATP8 Monoclonal Antibody (mMDQ)
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Product Details
651140
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
mMDQ
Immunogen
Synthetic N-Terminus (24 Aa) Of Human Organic Anion Transporter Oatp2
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
Specificity: OATP2 and OATP8, human organic anion transporters (90 kD, 120 kD, after SDS-PAGE).
Target Information
The OATPs (organic anion transporter polypeptides) are a family of transport proteins that have been found to mediate the uptake of organic ions into hepatocyte cells. These proteins fall into the solute carrier family 21A (SLC21A), and are expressed in liver, kidney, and brain. These polypeptides are involved in the excretion of potentially toxic compounds and therefore play a role in the overall detoxification system of the body. Unlike other members of the OATP family, OATP2 and 8 have been detected exclusively in the liver, and there is an 80% amino acid sequence homology between these polypeptides. Other names for OATP2 include SLC21A6, OATP-C, and LST-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Liver-specific organic anion transporter 1; Liver-specific organic anion transporter 2; liver-specific organic anion transporter 3TM13; LST-1; LST-2; OATP-2; OATP-8; OATP-C; OATP1B3; Organic anion transporter 8; organic anion transporter LST-3c; Organic anion transporter SLC21A6; Organic anion-transporting polypeptide 8; SLCO1B1; Sodium-independent organic anion-transporting polypeptide 2; solute carrier family 21 (organic anion transporter), member 6; solute carrier family 21 (organic anion transporter), member 8; Solute carrier family 21 member 6; Solute carrier family 21 member 8; Solute carrier organic anion transporter family member 1B1; Solute carrier organic anion transporter family member 1B3; solute carrier organic anion transporter family, member 1B1; solute carrier organic anion transporter family, member 1B3
Gene Aliases: HBLRR; LST-1; LST-2; LST-3TM13; LST1; LST2; LST3; OATP-8; OATP-C; OATP1B1; OATP1B3; OATP2; OATP8; OATPC; SLC21A6; SLC21A8; SLCO1B1; SLCO1B3
UniProt ID: (Human) Q9Y6L6, (Human) Q9NPD5
Entrez Gene ID: (Human) 10599, (Human) 28234
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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