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OAZ2 Antibody (PA5-103991) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded OAZ2 in rat liver tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with OAZ2 polyclonal antibody (Product # PA5-103991) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-103991
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human OAZ2(Accession O95190), corresponding to amino acid residues L119-P169.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2853322
Product Specific Information
Antibody detects endogenous levels of total OAZ2.
Target Information
Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: antizyme 2; AZ2; ODC-Az 2; Ornithine decarboxylase antizyme 2; Seizure-related protein 15
Gene Aliases: AZ-2; AZ2; OAZ2; Oaz2-ps; RGD1562933; Sez15
UniProt ID: (Human) O95190, (Mouse) O08608
Entrez Gene ID: (Human) 4947, (Mouse) 18247, (Rat) 501454
regulation of cellular amino acid metabolic process
polyamine metabolic process
polyamine biosynthetic process
negative regulation of catalytic activity
positive regulation of protein catabolic process
positive regulation of intracellular protein transport
negative regulation of polyamine transmembrane transport
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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