Proteintech

OCT1 Polyclonal Antibody

OCT1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 13

OCT1 Antibody (10387-1-AP) in ICC/IF

Immunofluorescent analysis of HeLa cells using 10387-1-AP (OCT1 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

OCT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

OCT1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

10387-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 10 publications 10 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:10-1:100

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

ChIP assay (ChIP)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Pig

Published species

Human, Mouse, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

OCT1 Fusion Protein Ag0586 (379-659 aa encoded by BC003571)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.23 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: RRKKRTSIE TNIRVALEKS FLENQKPTSE EITMIADQLN MEKEVIRVWF CNRRQKEKRI NPPSSGGTSS SPIKAIFPSP TSLVATTPSL VTSSAATTLT VSPVLPLTSA AVTNLSVTGT SDTTSNNTAT VISTAPPASS AVTSPSLSPS PSASASTSEA SSASETSTTQ TTSTPLSSPL GTSQVMVTAS GLQTAAAAAL QGAAQLPANA SLAAMAAAAG LNPSLMAPSQ FAAGGALLSL NPGTLSGALS PALMSNSTLA TIQALASGGS LPITSLDATG NL (379-659 aa encoded by BC003571)

Target Information

OCT1 (POU2F1) is a ubiquitously expressed transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. It modulates transcription transactivation by NR3C1, AR and PGR. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Ferulic acid supplementation alleviates hyperuricemia in high-fructose/fat diet-fed rats via promoting uric acid excretion and mediating the gut microbiota.

Food & function

Zhang N,Zhou J,Zhao L,Zhao Z,Wang S,Zhang L,Zhou F

Mon Feb 06 00:00:00 UTC 2023

MASTL is enriched in cancerous and pluripotent stem cells and influences OCT1/OCT4 levels.

iScience

Närvä E,Taskinen ME,Lilla S,Isomursu A,Pietilä M,Weltner J,Isola J,Sihto H,Joensuu H,Zanivan S,Norman J,Ivaska J

Fri Jun 17 00:00:00 UTC 2022

POU2F1 Promotes Cell Viability and Tumor Growth in Gastric Cancer through Transcriptional Activation of lncRNA TTC3-AS1.

Journal of oncology

Wang J,Xiao K,Hou F,Tang L,Luo D,Liu G,Wang Z

Thu Jul 15 00:00:00 UTC 2021

The POU2F1/miR-4490/USP22 axis regulates cell proliferation and metastasis in gastric cancer.

Cellular oncology (Dordrecht, Netherlands)

Xiao Y,Liu S,Li J,Dai W,Tang W,Xiang L,Zhang W,Lin J,Wang J,Wu X,Liu G,Liu Y,Chen Y,Zhu H,Wang Y,Lin Z,Yang Q,Chen T,Sun Y,Li A,Xiong J,Wang J

Tue Dec 01 00:00:00 UTC 2020

Susceptibility of rat immortalized neuronal cell line Rn33B expressing equine major histocompatibility class 1 to equine herpesvirus-1 infection is differentiation dependent.

Microbiology and immunology

Minato E,Kobayashi A,Aoshima K,Fukushi H,Kimura T

Sat Feb 01 00:00:00 UTC 2020

Anti-hyperuricemic potential of stevia (Stevia rebaudiana Bertoni) residue extract in hyperuricemic mice.

Food & function

Mehmood A,Zhao L,Ishaq M,Xin W,Zhao L,Wang C,Hossen I,Zhang H,Lian Y,Xu M

Wed Jul 22 00:00:00 UTC 2020

MiR-451a attenuates free fatty acids-mediated hepatocyte steatosis by targeting the thyroid hormone responsive spot 14 gene.

Molecular and cellular endocrinology

Zeng N,Huang R,Li N,Jiang H,Li R,Wang F,Chen W,Xia M,Wang Q

Mon Oct 15 00:00:00 UTC 2018

MiR-451a attenuates free fatty acids-mediated hepatocyte steatosis by targeting the thyroid hormone responsive spot 14 gene.

Molecular and cellular endocrinology

Zeng N,Huang R,Li N,Jiang H,Li R,Wang F,Chen W,Xia M,Wang Q

Mon Oct 15 00:00:00 UTC 2018

The farnesoid X receptor agonist obeticholic acid upregulates biliary excretion of asymmetric dimethylarginine via MATE-1 during hepatic ischemia/reperfusion injury.

PloS one

Ferrigno A,Di Pasqua LG,Berardo C,Siciliano V,Rizzo V,Adorini L,Richelmi P,Vairetti M

Fri Mar 09 00:00:00 UTC 2018

The farnesoid X receptor agonist obeticholic acid upregulates biliary excretion of asymmetric dimethylarginine via MATE-1 during hepatic ischemia/reperfusion injury.

PloS one

Ferrigno A,Di Pasqua LG,Berardo C,Siciliano V,Rizzo V,Adorini L,Richelmi P,Vairetti M

Fri Mar 09 00:00:00 UTC 2018

POU2F1 over-expression correlates with poor prognoses and promotes cell growth and epithelial-to-mesenchymal transition in hepatocellular carcinoma.

Oncotarget

Zhong Y,Huang H,Chen M,Huang J,Wu Q,Yan GR,Chen D

Tue Jul 04 00:00:00 UTC 2017

Oncogenic role of the TP53-induced glycolysis and apoptosis regulator in nasopharyngeal carcinoma through NF-κB pathway modulation.

International journal of oncology

Zhao M,Fan J,Liu Y,Yu Y,Xu J,Wen Q,Zhang J,Fu S,Wang B,Xiang L,Feng J,Wu J,Yang L

Mon Feb 01 00:00:00 UTC 2016

Oncogenic role of the TP53-induced glycolysis and apoptosis regulator in nasopharyngeal carcinoma through NF-κB pathway modulation.

International journal of oncology

Zhao M,Fan J,Liu Y,Yu Y,Xu J,Wen Q,Zhang J,Fu S,Wang B,Xiang L,Feng J,Wu J,Yang L

Mon Feb 01 00:00:00 UTC 2016

Aging increases the susceptibility of cisplatin-induced nephrotoxicity.

Age (Dordrecht, Netherlands)

Wen J,Zeng M,Shu Y,Guo D,Sun Y,Guo Z,Wang Y,Liu Z,Zhou H,Zhang W

Tue Dec 01 00:00:00 UTC 2015

Aging increases the susceptibility of cisplatin-induced nephrotoxicity.

Age (Dordrecht, Netherlands)

Wen J,Zeng M,Shu Y,Guo D,Sun Y,Guo Z,Wang Y,Liu Z,Zhou H,Zhang W

Tue Dec 01 00:00:00 UTC 2015

Long-term artificial selection reveals a role of TCTP in autophagy in mammalian cells.

Molecular biology and evolution

Chen K,Huang C,Yuan J,Cheng H,Zhou R

Fri Aug 01 00:00:00 UTC 2014

Long-term artificial selection reveals a role of TCTP in autophagy in mammalian cells.

Molecular biology and evolution

Chen K,Huang C,Yuan J,Cheng H,Zhou R

Fri Aug 01 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: NF-A1; Oct-1; octamer binding protein 1; Octamer-binding protein 1; Octamer-binding transcription factor 1; Octamer-binding transcription factor-1; OTF-1; POU domain, class 2, transcription factor 1

View more View less

Gene Aliases: oct-1B; OCT1; OTF1; POU2F1

View more View less

UniProt ID: (Human) P14859, (Pig) Q29076

View more View less

Entrez Gene ID: (Human) 5451, (Pig) 397501

View more View less

Function(s)

transcription regulatory region sequence-specific DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding receptor binding protein binding sequence-specific DNA binding

Process(es)

snRNA transcription from RNA polymerase II promoter negative regulation of transcription, DNA-templated liver regeneration

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

OCT1 Polyclonal Antibody

OCT1 Antibody (10387-1-AP) in ICC/IF

Product Details

10387-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

ChIP assay (ChIP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!