Proteintech

ODC1 Polyclonal Antibody

FIGURE: 1 / 1

ODC1 Antibody (28728-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with 28728-1-AP (ODC1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

Product Image Gallery

Product Details

28728-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 11 publications 11 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ODC1 fusion protein Ag29751

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

233 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Aliquoting is unnecessary for -20°C storage.

Target Information

Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

p53 inhibits the Urea cycle and represses polyamine biosynthesis in glioma cell lines.

Metabolic brain disease

Zhao Y,Chen Y,Wei L,Ran J,Wang K,Zhu S,Liu Q

Sat Apr 01 00:00:00 UTC 2023

Triptolide attenuates irritable bowel syndrome via inhibiting ODC1.

BMC gastroenterology

Zhu N,Zhu L,Zhang X,Huang C,Xiang W,Huang B

Mon Jun 12 00:00:00 UTC 2023

Human Chorionic Gonadotropin-Stimulated Interleukin-4-Induced-1 (IL4I1) Promotes Human Decidualization via Aryl Hydrocarbon Receptor.

International journal of molecular sciences

Luo JM,Zhang TT,He YY,Luo HN,Hong YQ,Yang ZM

Sun Feb 05 00:00:00 UTC 2023

A search for acrolein scavengers among food components.

Amino acids

Uemura T,Uchida M,Nakamura M,Shimekake M,Sakamoto A,Terui Y,Higashi K,Ishii I,Kashiwagi K,Igarashi K

Sat Apr 01 00:00:00 UTC 2023

Compromised glycolysis contributes to foot process fusion of podocytes in diabetic kidney disease: Role of ornithine catabolism.

Metabolism: clinical and experimental

Luo Q,Liang W,Zhang Z,Zhu Z,Chen Z,Hu J,Yang K,Chi Q,Ding G

Thu Sep 01 00:00:00 UTC 2022

SMARCE1 promotes neuroblastoma tumorigenesis through assisting MYCN-mediated transcriptional activation.

Oncogene

Hu X,Liu R,Hou J,Peng W,Wan S,Xu M,Li Y,Zhang G,Zhai X,Liang P,Cui H

Thu Sep 01 00:00:00 UTC 2022

Urea transporter B downregulates polyamines levels in melanoma B16 cells via p53 activation.

Biochimica et biophysica acta. Molecular cell research

Li J,Sun Y,Yan R,Wu X,Zou H,Meng Y

Sun May 01 00:00:00 UTC 2022

CDC27-ODC1 Axis Promotes Metastasis, Accelerates Ferroptosis and Predicts Poor Prognosis in Neuroblastoma.

Frontiers in oncology

Qiu L,Zhou R,Luo Z,Wu J,Jiang H

Sat Mar 05 00:00:00 UTC 2022

Targeting RNA editing of antizyme inhibitor 1: A potential oligonucleotide-based antisense therapy for cancer.

Molecular therapy : the journal of the American Society of Gene Therapy

Tay DJT,Song Y,Peng B,Toh TB,Hooi L,Toh DK,Hong H,Tang SJ,Han J,Gan WL,Chan THM,Krishna MS,Patil KM,Maraswami M,Loh TP,Dan YY,Zhou L,Bonney GK,Chow PK,Chen G,Chow EK,Le MTN,Chen L

Wed Nov 03 00:00:00 UTC 2021

Correlation of polyamines, acrolein-conjugated lysine and polyamine metabolic enzyme levels with age in human liver.

Heliyon

Uemura T,Akasaka Y,Ikegaya H

Tue Sep 01 00:00:00 UTC 2020

Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells.

OncoTargets and therapy

Zeng Z,Lan J,Lei S,Yang Y,He Z,Xue Y,Chen T

Mon Apr 18 00:00:00 UTC 2022

Ornithine decarboxylase, the rate-limiting enzyme of polyamine synthesis, modifies brain pathology in a mouse model of tuberous sclerosis complex.

Human molecular genetics

Kapfhamer D,McKenna J,Yoon CJ,Murray-Stewart T,Casero RA,Gambello MJ

Tue Aug 11 00:00:00 UTC 2020

Polyamine regulation of porcine reproductive and respiratory syndrome virus infection depends on spermidine-spermine acetyltransferase 1.

Veterinary microbiology

Zhou Y,Hou Z,Fang L,Ke Q,Xiong Y,Fang P,Xiao S

Sun Nov 01 00:00:00 UTC 2020

Bioinformatics

Protein Aliases: MGC103389; ODC; Ornithine decarboxylase

View more View less

Gene Aliases: ODC; ODC1

View more View less

UniProt ID: (Human) P11926, (Mouse) P00860

View more View less

Entrez Gene ID: (Human) 4953, (Mouse) 18263

View more View less

Function(s)

ornithine decarboxylase activity protein binding protein homodimerization activity catalytic activity lyase activity carboxy-lyase activity

Process(es)

kidney development regulation of cellular amino acid metabolic process polyamine metabolic process positive regulation of cell proliferation response to virus putrescine biosynthetic process from ornithine regulation of protein catabolic process polyamine biosynthetic process putrescine biosynthetic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

ODC1 Polyclonal Antibody

ODC1 Antibody (28728-1-AP) in WB

Product Details

28728-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!