Proteintech

OIP5 Polyclonal Antibody

View all (23) OIP5 antibodies

Questions & Answers

Questions & Answers

Antibody Testing Data (6)

OIP5 Antibody in Western Blot (WB)

OIP5 Antibody in Western Blot (WB)

FIGURE: 1 / 6

OIP5 Antibody (12142-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with (Product # 12142-1-AP) OIP5 antibody at dilution of 1:2,000 incubated at room temperature for 1.5 hours.

OIP5 Antibody in Western Blot (WB)

OIP5 Antibody in Western Blot (WB)

OIP5 Antibody in Western Blot (WB)

OIP5 Antibody in Western Blot (WB)

OIP5 Antibody in Western Blot (WB)

OIP5 Antibody in Immunoprecipitation (IP)

Product Image Gallery

OIP5 Antibody in Western Blot (WB) — Various lysates were subjected to SDS PAGE followed by western blot with (Product # 12142-1-AP) OIP5 antibody at dilution of 1:2,000 incubated at room temperature for 1.5 hours.

OIP5 Antibody in Western Blot (WB) — Jurkat cells were subjected to SDS PAGE followed by western blot with 12142-1-AP (OIP5 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours.

OIP5 Antibody in Western Blot (WB) — Jurkat cells were subjected to SDS PAGE followed by western blot with 12142-1-AP (OIP5 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

OIP5 Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 12142-1-AP (OIP5 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

OIP5 Antibody in Western Blot (WB) — PC-3 cells were subjected to SDS PAGE followed by western blot with 12142-1-AP (OIP5 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

OIP5 Antibody in Immunoprecipitation (IP) — IP result of anti-OIP5 (IP:12142-1-AP, 3ug; Detection:12142-1-AP 1:500) with Jurkat cells lysate 3200ug.

Product Details

12142-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 8 publications 8 publications

Immunohistochemistry (IHC)

Assay-dependent

View 4 publications 4 publications

Immunocytochemistry (ICC/IF)

-

View 3 publications 3 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

OIP5 Fusion Protein Ag2790 (1-229 aa encoded by BC015050)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAAQPLRHR SRCATPPRGD FCGGTERAID QASFTTSMEW DTQVVKGSSP LGPAGLGAEE PAAGPQLPSW LQPERCAVFQ CAQCHAVLAD SVHLAWDLSR SLGAVVFSRV TNNVVLEAPF LVGIEGSLKG STYNLLFCGS CGIPVGFHLY STHAALAALR GHFCLSSDKM VCYLLKTKAI VNASEMDIQN VPLSEKIAEL KEKIVLTHNR LKSLMKILSE VTPDQSKPEN (1-229 aa encoded by BC015050)

Target Information

Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Characterization of Opa interacting protein 5 as a new biomarker and therapeutic target for oral cancer.

International journal of oncology

Zhu M,Takano A,Tsevegjav B,Yoshitake Y,Shinohara M,Daigo Y

Tue Mar 01 00:00:00 UTC 2022

Characterization of Opa interacting protein 5 as a new biomarker and therapeutic target for oral cancer.

International journal of oncology

Zhu M,Takano A,Tsevegjav B,Yoshitake Y,Shinohara M,Daigo Y

Tue Mar 01 00:00:00 UTC 2022

Characterization of Opa interacting protein 5 as a new biomarker and therapeutic target for oral cancer.

International journal of oncology

Zhu M,Takano A,Tsevegjav B,Yoshitake Y,Shinohara M,Daigo Y

Tue Mar 01 00:00:00 UTC 2022

Overexpression of Opa interacting protein 5 increases the progression of liver cancer via BMPR2/JUN/CHEK1/RAC1 dysregulation.

Oncology reports

Li Y,Xiao F,Li W,Hu P,Xu R,Li J,Li G,Zhu C

Mon Apr 01 00:00:00 UTC 2019

Cancer-testis specific gene OIP5: a downstream gene of E2F1 that promotes tumorigenesis and metastasis in glioblastoma by stabilizing E2F1 signaling.

Neuro-oncology

He J,Zhao Y,Zhao E,Wang X,Dong Z,Chen Y,Yang L,Cui H

Thu Aug 02 00:00:00 UTC 2018

Opa-interacting protein 5 modulates docetaxel-induced cell death via regulation of mitophagy in gastric cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Kim TW,Lee SJ,Park YJ,Park SY,Oh BM,Park YS,Kim BY,Lee YH,Cho HJ,Yoon SR,Choe YK,Lee HG

Sun Oct 01 00:00:00 UTC 2017

Opa-interacting protein 5 modulates docetaxel-induced cell death via regulation of mitophagy in gastric cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Kim TW,Lee SJ,Park YJ,Park SY,Oh BM,Park YS,Kim BY,Lee YH,Cho HJ,Yoon SR,Choe YK,Lee HG

Sun Oct 01 00:00:00 UTC 2017

Opa-interacting protein 5 modulates docetaxel-induced cell death via regulation of mitophagy in gastric cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Kim TW,Lee SJ,Park YJ,Park SY,Oh BM,Park YS,Kim BY,Lee YH,Cho HJ,Yoon SR,Choe YK,Lee HG

Sun Oct 01 00:00:00 UTC 2017

Opa-interacting protein 5 modulates docetaxel-induced cell death via regulation of mitophagy in gastric cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Kim TW,Lee SJ,Park YJ,Park SY,Oh BM,Park YS,Kim BY,Lee YH,Cho HJ,Yoon SR,Choe YK,Lee HG

Sun Oct 01 00:00:00 UTC 2017

Opa-interacting protein 5 modulates docetaxel-induced cell death via regulation of mitophagy in gastric cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Kim TW,Lee SJ,Park YJ,Park SY,Oh BM,Park YS,Kim BY,Lee YH,Cho HJ,Yoon SR,Choe YK,Lee HG

Sun Oct 01 00:00:00 UTC 2017

Opa-interacting protein 5 modulates docetaxel-induced cell death via regulation of mitophagy in gastric cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Kim TW,Lee SJ,Park YJ,Park SY,Oh BM,Park YS,Kim BY,Lee YH,Cho HJ,Yoon SR,Choe YK,Lee HG

Sun Oct 01 00:00:00 UTC 2017

Opa-interacting protein 5 modulates docetaxel-induced cell death via regulation of mitophagy in gastric cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Kim TW,Lee SJ,Park YJ,Park SY,Oh BM,Park YS,Kim BY,Lee YH,Cho HJ,Yoon SR,Choe YK,Lee HG

Sun Oct 01 00:00:00 UTC 2017

OIP5, a target of miR-15b-5p, regulates hepatocellular carcinoma growth and metastasis through the AKT/mTORC1 and β-catenin signaling pathways.

Oncotarget

Li H,Zhang J,Lee MJ,Yu GR,Han X,Kim DG

Tue Mar 14 00:00:00 UTC 2017

OIP5, a target of miR-15b-5p, regulates hepatocellular carcinoma growth and metastasis through the AKT/mTORC1 and β-catenin signaling pathways.

Oncotarget

Li H,Zhang J,Lee MJ,Yu GR,Han X,Kim DG

Tue Mar 14 00:00:00 UTC 2017

Mitotic regulator Mis18β interacts with and specifies the centromeric assembly of molecular chaperone holliday junction recognition protein (HJURP).

The Journal of biological chemistry

Wang J,Liu X,Dou Z,Chen L,Jiang H,Fu C,Fu G,Liu D,Zhang J,Zhu T,Fang J,Zang J,Cheng J,Teng M,Ding X,Yao X

Fri Mar 21 00:00:00 UTC 2014

Mitotic regulator Mis18β interacts with and specifies the centromeric assembly of molecular chaperone holliday junction recognition protein (HJURP).

The Journal of biological chemistry

Wang J,Liu X,Dou Z,Chen L,Jiang H,Fu C,Fu G,Liu D,Zhang J,Zhu T,Fang J,Zang J,Cheng J,Teng M,Ding X,Yao X

Fri Mar 21 00:00:00 UTC 2014

Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity.

International journal of nanomedicine

Yuan Q,Han J,Cong W,Ge Y,Ma D,Dai Z,Li Y,Bi X

Tue Jun 02 00:00:00 UTC 2015

Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity.

International journal of nanomedicine

Yuan Q,Han J,Cong W,Ge Y,Ma D,Dai Z,Li Y,Bi X

Tue Jun 02 00:00:00 UTC 2015

Expression of Opa interacting protein 5 (OIP5) is associated with tumor stage and prognosis of clear cell renal cell carcinoma.

Acta histochemica

Gong M,Xu Y,Dong W,Guo G,Ni W,Wang Y,Wang Y,An R

Tue Oct 01 00:00:00 UTC 2013

Expression of Opa interacting protein 5 (OIP5) is associated with tumor stage and prognosis of clear cell renal cell carcinoma.

Acta histochemica

Gong M,Xu Y,Dong W,Guo G,Ni W,Wang Y,Wang Y,An R

Tue Oct 01 00:00:00 UTC 2013

Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.

Cancer science

Koinuma J,Akiyama H,Fujita M,Hosokawa M,Tsuchiya E,Kondo S,Nakamura Y,Daigo Y

Thu Mar 01 00:00:00 UTC 2012

Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.

Cancer science

Koinuma J,Akiyama H,Fujita M,Hosokawa M,Tsuchiya E,Kondo S,Nakamura Y,Daigo Y

Thu Mar 01 00:00:00 UTC 2012

Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.

Cancer science

Koinuma J,Akiyama H,Fujita M,Hosokawa M,Tsuchiya E,Kondo S,Nakamura Y,Daigo Y

Thu Mar 01 00:00:00 UTC 2012

Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.

Cancer science

Koinuma J,Akiyama H,Fujita M,Hosokawa M,Tsuchiya E,Kondo S,Nakamura Y,Daigo Y

Thu Mar 01 00:00:00 UTC 2012

Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.

Cancer science

Koinuma J,Akiyama H,Fujita M,Hosokawa M,Tsuchiya E,Kondo S,Nakamura Y,Daigo Y

Thu Mar 01 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: Cancer/testis antigen 86; CT86; LAP2alpha interactor-25; MIS18 kinetochore protein homolog B; OIP-5; Opa-interacting protein 5; Protein Mis18-beta

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Gene Aliases: 5730547N13Rik; CT86; hMIS18beta; LINT-25; MIS18B; MIS18beta; OIP5

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UniProt ID: (Human) O43482

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Entrez Gene ID: (Human) 11339

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protein binding metal ion binding

mitotic nuclear division cell communication CENP-A containing nucleosome assembly cell division

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