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This gene encodes a member of the olfactomedin-like gene family which also includes genes encoding noelin, tiarin, myocilin, amassin, optimedin, photomedin, and latrophilin. The encoded protein is a secreted extracellular matrix glycoprotein with a C-terminal olfactomedin domain that facilitates protein-protein interactions, cell adhesion, and intercellular interactions. It serves as both a scaffold protein that recruits bone morphogenetic protein 1 to its substrate chordin, and as a vascular tissue remodeler with pro-angiogenic properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017].
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Protein Aliases: HNOEL-iso; hOLF44; olfactomedin-like 3; Olfactomedin-like protein 3
Gene Aliases: HNOEL-iso; OLF44; OLFML3; PSEC0035; PSEC0173; PSEC0244; UNQ663/PRO1294
UniProt ID: (Human) Q9NRN5
Entrez Gene ID: (Human) 56944, (Rat) 310743
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