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Invitrogen
OPRD1 Recombinant Rabbit Monoclonal Antibody (SN20-04)
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Product Details
MA5-32338
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
SN20-04
Immunogen
Synthetic peptide within Human OPRD1 aa 1-50
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2809619
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
OPRD1 is an Opioid Receptor that is involved in the control of anxiety, depression, and pain. It is a promising target in the therapy of mood-altering disorders and drug addiction. Delta and kappa opioid receptors function synergistically by forming heterodimers. OPRD1 expression has been reported primarily in the brain. High OPRD1 expression has been documented in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low OPRD1 expression has been identified in the cerebellum, hypothalamus, substantia nigra, and thalamus. OPRD1 expression is reduced in the putamen and amygdala of Alzheimer's patients and in the putamen in Parkinson's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: D-OR-1; delta 1 opioid receptor; delta opioid receptor 1; Delta-type opioid receptor; DOR-1; K56; MSL-2; Opioid receptor; Opioid receptor A; opioid receptor, delta 1
Gene Aliases: DOR; DOR-1; mDOR; Nbor; OPRD; OPRD1; Ror-a
UniProt ID: (Human) P41143, (Mouse) P32300, (Rat) P33533
Entrez Gene ID: (Human) 4985, (Mouse) 18386, (Rat) 24613
protein import into nucleus, translocation
immune response
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
chemical synaptic transmission
adult locomotory behavior
negative regulation of gene expression
sensory perception of pain
negative regulation of protein oligomerization
positive regulation of CREB transcription factor activity
positive regulation of peptidyl-serine phosphorylation
opioid receptor signaling pathway
eating behavior
regulation of mitochondrial membrane potential
regulation of calcium ion transport
regulation of sensory perception of pain
cellular response to growth factor stimulus
cellular response to hypoxia
cellular response to toxic substance
signal transduction
adenylate cyclase-activating dopamine receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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