Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: SQKIQAQNR VVSAPVGKET PSKRMKRDKT SDLVEEYFEA HSSSKVLTSD RTLQKLKRAK LDQQTLRNLL SKVSPSFSAE LKQLNQQYEK LFHKWMLQLH LGFNIVLYGL GSKRDLLERF RTTMLQDSIH VVINGFFPGI SVKSVLNSIT EEVLDHMGTF RSILDQLDWI VNKFKEDSSL ELFLLIHNLD SQMLRGEKSQ QIIGQLSSLH NIYLIASIDH LNAPLMWDHA KQSLFNWLWY ETTTYSPYTE ETSYENSLLV KQSGSLPLSS LTHVLRSLTP NARGIFRLLI KYQLDNQDNP SYIGLSFQDF YQQCREAFLV NSDLTLRAQL TEFRDHKLIR TKKGTDGVEY LLIPVDNGTL TDFLEKEEEE A (208-578 aa encoded by BC014834)
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: origin recognition complex protein 2 homolog; Origin recognition complex subunit 2; origin recognition complex, subunit 2 homolog; origin recognition complex, subunit 2-like
Gene Aliases: AU041563; ORC2; ORC2L
UniProt ID: (Human) Q13416, (Rat) Q75PQ8, (Mouse) Q60862
Entrez Gene ID: (Human) 4999, (Rat) 301430, (Mouse) 18393
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