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Invitrogen
ORC3 Polyclonal Antibody
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FIGURE: 1 / 1
ORC3 Antibody (PA5-90450) in WB
Western blot analysis of ORC3 in extracts of various cell lines. Samples were incubated with ORC3 Polyclonal antibody (Product # PA5-90450) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-90450
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ORC3 (NP_0365132)
Conjugate
Form
Liquid
Concentration
2.19 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806082
Product Specific Information
Immunogen sequence: MATSSMSKGC FVFKPNSKKR KISLPIEDYF NKGKNEPEDS KLRFETYQLI WQQMKSENER LQEELNKNLF DNLIEFLQKS HSGFQKNSRD LGGQIKLREI PTAALVLGVN VTDHDLTFGS LTEALQNNVT PYVVSLQAKD CPDMKHFLQK LISQLMDCCV DIKSKEEESV HVTQRKTHYS MDSLSSWYMT VTQKTDPKML SKKRTTSSQW QSPPVVVILK DMESFATKVL QDFIIISSQH; Positive Samples: LO2, 293T, HeLa, Mouse liver; Cellular Location: Nucleus
Target Information
Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homolog of latheo, Drosophila; IMAGE50150; origin of replication 3 homolog; Origin recognition complex subunit 3; Origin recognition complex subunit Latheo; origin recognition complex, subunit 3 honolog; origin recognition complex, subunit 3-like; OTTHUMP00000040611; RP3-486L4.1
Gene Aliases: LAT; LATHEO; ORC3; ORC3L
UniProt ID: (Human) Q9UBD5, (Rat) Q4R180, (Mouse) Q9JK30
Entrez Gene ID: (Human) 23595, (Rat) 313138, (Mouse) 50793
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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