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Invitrogen
ORP8 Polyclonal Antibody
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Product Details
PA5-107205
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human OSBPL8 (aa 797-847)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.4, with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2817921
Product Specific Information
Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Target Information
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ORP-8; OSBP-related protein 8; Oxysterol-binding protein-related protein 8
Gene Aliases: KIAA1451; MST120; MSTP120; ORP8; OSBP10; OSBPL8
UniProt ID: (Human) Q9BZF1
Entrez Gene ID: (Human) 114882
negative regulation of sequestering of triglyceride
phospholipid transport
negative regulation of cell migration
activation of protein kinase B activity
fat cell differentiation
positive regulation of insulin receptor signaling pathway
positive regulation of protein kinase B signaling
protein localization to nuclear pore
positive regulation of glucose import in response to insulin stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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