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Invitrogen
ORP8 Polyclonal Antibody
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ORP8 Antibody (PA5-110065) in IHC (P)
Immunohistochemistry analysis of ORP8 in paraffin-embedded human esophageal. Samples were incubated with ORP8 Polyclonal antibody (Product # PA5-110065) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-110065
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human OSBPL8 (NP_065892.1).
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2855476
Product Specific Information
Immunogen sequence: MEGGLADGEP DRTSLLGDSK DVLGPSTVVA NSDESQLLTP GKMSQRQGKE AYPTPTKDLH QPSLSPASPH SQGFERGKED ISQNKDESSL SMSKSKSESK LYNGSEKDSS
Target Information
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ORP-8; OSBP-related protein 8; Oxysterol-binding protein-related protein 8
Gene Aliases: AA536976; AA536995; C730029P18Rik; D330025H14Rik; KIAA1451; MST120; MSTP120; ORP-8; ORP8; OSBP10; OSBPL8; RGD1561474
UniProt ID: (Human) Q9BZF1, (Mouse) B9EJ86
Entrez Gene ID: (Human) 114882, (Mouse) 237542, (Rat) 314824
negative regulation of sequestering of triglyceride
phospholipid transport
negative regulation of cell migration
activation of protein kinase B activity
fat cell differentiation
positive regulation of insulin receptor signaling pathway
positive regulation of protein kinase B signaling
protein localization to nuclear pore
positive regulation of glucose import in response to insulin stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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