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Invitrogen
OSTM1 Polyclonal Antibody
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FIGURE: 1 / 1
OSTM1 Antibody (PA5-120130) in WB
Western blot analysis of OSTM1 in extracts of various cell lines. Samples were incubated with OSTM1 Polyclonal antibody (Product # PA5-120130) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-120130
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 32-284 of human OSTM1 (NP_054747.2).
Conjugate
Form
Liquid
Concentration
3.79 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2913702
Product Specific Information
Positive test controls include: HeLa, 293T, A-549, Raji, B cells, Mouse brain, Mouse kidney. The target is usually found in the following locations: Lysosome membrane, Single-pass type I membrane protein.
Immunogen sequence: ALPFGSSPHR VFHDLLSEQQ LLEVEDLSLS LLQGGGLGPL SLPPDLPDLD PECRELLLDF ANSSAELTGC LVRSARPVRL CQTCYPLFQQ VVSKMDNISR AAGNTSESQS CARSLLMADR MQIVVILSEF FNTTWQEANC ANCLTNNSEE LSNSTVYFLN LFNHTLTCFE HNLQGNAHSL LQTKNYSEVC KNCREAYKTL SSLYSEMQKM NELENKAEPG THLCIDVEDA MNITRKLWSR TFNCSVPCSD TVP
Target Information
This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chloride channel 7 beta subunit; CLCN7 accessory beta subunit; GAIP-interacting protein N terminus; grey lethal osteopetrosis; grey-lethal osteopetrosis; Grey-lethal protein; Osteopetrosis-associated transmembrane protein 1
Gene Aliases: 1200002H13Rik; GIPN; GL; HSPC019; OPTB5; OSTM1; UNQ6098/PRO21201
UniProt ID: (Human) Q86WC4, (Mouse) Q8BGT0
Entrez Gene ID: (Human) 28962, (Mouse) 14628
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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