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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • OTC Antibodies

          Invitrogen

          OTC Monoclonal Antibody (CL4045)

          Advanced Verification
          View all (66) OTC antibodies

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          Datasheet
          Protocols
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          Datasheet
          Protocols
          Questions & Answers

          Cite OTC Monoclonal Antibody (CL4045)

          • Antibody Testing Data (5)
          • Advanced Verification (1)
          OTC Antibody in Immunocytochemistry (ICC/IF)
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          OTC Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 6

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          OTC Antibody (MA5-31396) in ICC/IF

          Immunofluorecent analysis of OTC in RH-30 cells using OTC Monoclonal Antibody (CL4045) (Product # MA5-31396). Staining shows specific staining in mitochondria in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          OTC Antibody in Immunocytochemistry (ICC/IF)
          OTC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          OTC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          OTC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          OTC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          OTC Antibody

          Product Details

          MA5-31396

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:10,000-1:20,000
          -

          Immunocytochemistry (ICC/IF)

          2-10 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG2a

          Class

          Monoclonal

          Type

          Antibody

          Clone

          CL4045

          Immunogen

          Recombinant protein corresponding to Human OTC
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2787032

          Product Specific Information

          Immunogen sequence: ILADYLTLQE HYSSLKGLTL SWIGDGNNIL HSIMMSAAKF GMHLQAATPK GYEPDASVTK LAEQYAKENG TKLLLTNDPL EAAHGGNVLI TDTWISMGQE EEKKKRLQAF QGYQVTMKTA KVAASDWT

          Target Information

          This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Ornithine carbamoyltransferase, mitochondrial; ornithine transcarbamylase; Ornithine transcarbamylase, mitochondrial; OTCase

          View more View less

          Gene Aliases: OCTD; OTC

          View more View less

          UniProt ID: (Human) P00480

          View more View less

          Entrez Gene ID: (Human) 5009

          View more View less

          Function(s)
          ornithine carbamoyltransferase activity phospholipid binding amino acid binding phosphate ion binding
          Process(es)
          urea cycle liver development ornithine catabolic process midgut development response to zinc ion citrulline biosynthetic process response to insulin arginine biosynthetic process via ornithine response to drug anion homeostasis protein homotrimerization response to biotin ammonia homeostasis
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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