Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: PFNIEYQIL ASTMLYVLWK NIGRKVDSHQ HQKMQFKSDG VMVGAVLGLT VLAATIAVVV VYLIHIGRSK TKSESALIMF YLYAITLLML MGAAGLAGIR IYRIDEKSLD ESKNPARKLD SDLLVGTASG SWLISWGSIL AILCAEGHPR YTWYNLPYSI LAIVEKYIQN LFIFESIHRE PEKLSEDIQT LRVVTVCNGN TMPLASSCPK SGGVARDVAP QGKDMPPAAN GNVCMRESHD KEEEKQEESS WGGSPSPVRL PRFLQGNAKR KVLRNIAAFL FLCNISLWIP PAFGCRPEYD NGLEEIVFGF EPWIIVVNLA MPFSIFYRMH AAASLFEVYC KI (272-612 aa encoded by BC130430)
Required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hOtop1; Otopetrin-1; Proton channel OTOP1; tilted
Gene Aliases: A530025J20Rik; OTOP1; Otp1; tlt
UniProt ID: (Human) Q7RTM1, (Mouse) Q80VM9
Entrez Gene ID: (Human) 133060, (Mouse) 21906
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