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OTOP1 Antibody (AHC-005-200UL) in IHC (F)
Expression of Otopetrin-1 in mouse hippocampus. Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-Otopetrin-1 Antibody (#AHC-005), (1:300), followed by goat Anti-rabbit-AlexaFluor-488. A. Staining in the mouse hippocampal CA1 region, showed Otopetrin-1 immunoreactivity (green) in astrocytic profiles (arrows). B. Pre-incubation of the Antibody with Otopetrin-1 Blocking Pep... View More
Product Details
AHC-005-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)EKSLDESKNPARKLD, corresponding to amino acid residues 374-388 of mouse Otopetrin-1, 4thintracellular loop
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hOtop1; Otopetrin-1; Proton channel OTOP1; tilted
Gene Aliases: A530025J20Rik; OTOP1; Otp1; tlt
UniProt ID: (Human) Q7RTM1, (Rat) Q7M734, (Mouse) Q80VM9
Entrez Gene ID: (Human) 133060, (Rat) 305427, (Mouse) 21906
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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