Invitrogen

OVOL2 Polyclonal Antibody

View all (11) OVOL2 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Product Details

PA5-115700

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human OVOL2(Accession Q9BRP0), corresponding to amino acid residues V200-L250.
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2900335

Product Specific Information

Antibody detects endogenous levels of total OVOL2.

Target Information

DNA-binding protein that binds to the 5'-G[GCT]GGGGG-3' core sequence. Probably acts as a transcription regulator.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: hOvo2; MOVO-B zinc finger protein; MOVO-C zinc finger protein; mOvo2; OVO homolog-like 2; ovo-like 2; Transcription factor Ovo-like 2; Zinc finger OVO2; Zinc finger protein 339; Zinc finger protein mOVO

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Gene Aliases: 1700108N11Rik; 1810007D21Rik; EUROIMAGE566589; M-OVO; M-OVO-A; M-OVO-B; MOVO; movo2; Ovo2; OVOL2; PPCD1; Zfp339; ZNF339

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UniProt ID: (Human) Q9BRP0, (Mouse) Q8CIV6

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Entrez Gene ID: (Human) 58495, (Rat) 296201, (Mouse) 107586

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Function(s)
RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding metal ion binding transcription regulatory region DNA binding nucleic acid binding transcription factor activity, sequence-specific DNA binding
Process(es)
angiogenesis neural crest cell migration neural fold formation heart looping regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter heart development negative regulation of cell proliferation epidermis development epidermal cell differentiation dorsal/ventral pattern formation negative regulation of epithelial to mesenchymal transition regulation of keratinocyte proliferation negative regulation of transcription by competitive promoter binding negative regulation of keratinocyte differentiation positive regulation of keratinocyte differentiation negative regulation of Notch signaling pathway negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated embryonic digestive tract morphogenesis regulation of cell cycle endocardium formation heart trabecula formation labyrinthine layer blood vessel development negative regulation of stem cell proliferation transcription, DNA-templated regulation of transcription, DNA-templated multicellular organism development positive regulation of transcription from RNA polymerase II promoter
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