Product References
Tandem mass tag-based quantitative proteomic analysis identification of succinylation related proteins in pathogenesis of thoracic aortic aneurysm and aortic dissection.
PeerJ
Zhang Y,Zhang H,Wang H,Wang C,Yang P,Lu C,Liu Y,Xu Z,Xie Y,Hu J
Thu May 18 00:00:00 UTC 2023
Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice.
American journal of physiology. Endocrinology and metabolism
Rome FI,Shobert GL,Voigt WC,Stagg DB,Puchalska P,Burgess SC,Crawford PA,Hughey CC
Sun Jan 01 00:00:00 UTC 2023
The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase.
Diabetes
Tabatabaei Dakhili SA,Greenwell AA,Yang K,Abou Farraj R,Saed CT,Gopal K,Chan JSF,Chahade JJ,Eaton F,Lee C,Velázquez-Martínez CA,Crawford PA,Glover JNM,Al Batran R,Ussher JR
Sun Jan 01 00:00:00 UTC 2023
Neuroprotective mechanisms of OXCT1 via the SIRT3-SOD2 pathway after traumatic brain injury.
Brain research
Zhuang YS,Wang X,Gao SQ,Miao SH,Li T,Gao CC,Han YL,Qiu JY,Zhou ML,Wang HD
Thu Jun 01 00:00:00 UTC 2023
Neuroprotective mechanisms of OXCT1 via the SIRT3-SOD2 pathway after traumatic brain injury.
Brain research
Zhuang YS,Wang X,Gao SQ,Miao SH,Li T,Gao CC,Han YL,Qiu JY,Zhou ML,Wang HD
Thu Jun 01 00:00:00 UTC 2023
Ketogenic diet modulates cardiac metabolic dysregulation in streptozocin-induced diabetic rats.
The Journal of nutritional biochemistry
Trang NN,Lee TW,Kao YH,Chao TF,Lee TI,Chen YJ
Sun Jan 01 00:00:00 UTC 2023
Defective muscle ketone body oxidation disrupts BCAA catabolism by altering mitochondrial branched-chain aminotransferase.
American journal of physiology. Endocrinology and metabolism
Mechchate H,Abdualkader AM,Bernacchi JB,Gopal K,Tabatabaei Dakhili SA,Yang K,Greenwell AA,Kong X,Crawford PA,Al Batran R
Mon May 01 00:00:00 UTC 2023
Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Tang M,Xu H,Huang H,Kuang H,Wang C,Li Q,Zhang X,Ge Y,Song M,Zhang X,Wang Z,Ma C,Kang J,Zhang W,Wang Y,Zhang B,Zhang X,Chen Y,Cong M,Melino G,Wang X,Zhou F,Sun Q,Shi H
Sat Oct 01 00:00:00 UTC 2022
Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Tang M,Xu H,Huang H,Kuang H,Wang C,Li Q,Zhang X,Ge Y,Song M,Zhang X,Wang Z,Ma C,Kang J,Zhang W,Wang Y,Zhang B,Zhang X,Chen Y,Cong M,Melino G,Wang X,Zhou F,Sun Q,Shi H
Sat Oct 01 00:00:00 UTC 2022
Exogenous ketone ester administration attenuates systemic inflammation and reduces organ damage in a lipopolysaccharide model of sepsis.
Biochimica et biophysica acta. Molecular basis of disease
Soni S,Martens MD,Takahara S,Silver HL,Maayah ZH,Ussher JR,Ferdaoussi M,Dyck JRB
Tue Nov 01 00:00:00 UTC 2022
Ketogenic diet uncovers differential metabolic plasticity of brain cells.
Science advances
Düking T,Spieth L,Berghoff SA,Piepkorn L,Schmidke AM,Mitkovski M,Kannaiyan N,Hosang L,Scholz P,Shaib AH,Schneider LV,Hesse D,Ruhwedel T,Sun T,Linhoff L,Trevisiol A,Köhler S,Pastor AM,Misgeld T,Sereda M,Hassouna I,Rossner MJ,Odoardi F,Ischebeck T,de Hoz L,Hirrlinger J,Jahn O,Saher G
Fri Sep 16 00:00:00 UTC 2022
Ketogenic diet uncovers differential metabolic plasticity of brain cells.
Science advances
Düking T,Spieth L,Berghoff SA,Piepkorn L,Schmidke AM,Mitkovski M,Kannaiyan N,Hosang L,Scholz P,Shaib AH,Schneider LV,Hesse D,Ruhwedel T,Sun T,Linhoff L,Trevisiol A,Köhler S,Pastor AM,Misgeld T,Sereda M,Hassouna I,Rossner MJ,Odoardi F,Ischebeck T,de Hoz L,Hirrlinger J,Jahn O,Saher G
Fri Sep 16 00:00:00 UTC 2022
Ketone body oxidation increases cardiac endothelial cell proliferation.
EMBO molecular medicine
Weis EM,Puchalska P,Nelson AB,Taylor J,Moll I,Hasan SS,Dewenter M,Hagenmüller M,Fleming T,Poschet G,Hotz-Wagenblatt A,Backs J,Crawford PA,Fischer A
Thu Apr 07 00:00:00 UTC 2022
Insight of a Metabolic Prognostic Model to Identify Tumor Environment and Drug Vulnerability for Lung Adenocarcinoma.
Frontiers in immunology
Peng SL,Wang R,Zhou YL,Wei W,Zhong GH,Huang XT,Yang S,Liu QD,Liu ZG
Tue Jul 12 00:00:00 UTC 2022
Barth syndrome-related cardiomyopathy is associated with a reduction in myocardial glucose oxidation.
American journal of physiology. Heart and circulatory physiology
Greenwell AA,Gopal K,Altamimi TR,Saed CT,Wang F,Tabatabaei Dakhili SA,Ho KL,Zhang L,Eaton F,Kruger J,Al Batran R,Lopaschuk GD,Oudit GY,Ussher JR
Tue Jun 01 00:00:00 UTC 2021
Pan-Cancer Analysis of Glycolytic and Ketone Bodies Metabolic Genes: Implications for Response to Ketogenic Dietary Therapy.
Frontiers in oncology
Qian L,Li Y,Cao Y,Meng G,Peng J,Li H,Wang Y,Xu T,Zhang L,Sun B,Li B,Yu D
Wed Apr 27 00:00:00 UTC 2022
Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation.
Cell metabolism
Al Batran R,Gopal K,Capozzi ME,Chahade JJ,Saleme B,Tabatabaei-Dakhili SA,Greenwell AA,Niu J,Almutairi M,Byrne NJ,Masson G,Kim R,Eaton F,Mulvihill EE,Garneau L,Masters AR,Desta Z,Velázquez-Martínez CA,Aguer C,Crawford PA,Sutendra G,Campbell JE,Dyck JRB,Ussher JR
Tue May 05 00:00:00 UTC 2020
WHSC1 Promotes Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Activating mTORC1 Signaling.
OncoTargets and therapy
Dai J,Jiang L,Qiu L,Shao Y,Shi P,Li J
Sat Apr 16 00:00:00 UTC 2022
Effects of a Ketogenic Diet Containing Medium-Chain Triglycerides and Endurance Training on Metabolic Enzyme Adaptations in Rat Skeletal Muscle.
Nutrients
Fukazawa A,Koike A,Karasawa T,Tsutsui M,Kondo S,Terada S
Thu Apr 30 00:00:00 UTC 2020
β-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle.
Nutrients
Monsalves-Alvarez M,Morales PE,Castro-Sepulveda M,Sepulveda C,Rodriguez JM,Chiong M,Eisner V,Lavandero S,Troncoso R
Mon Jun 29 00:00:00 UTC 2020
Trimetazidine Ameliorates Myocardial Metabolic Remodeling in Isoproterenol-Induced Rats Through Regulating Ketone Body Metabolism via Activating AMPK and PPAR α.
Frontiers in pharmacology
Li H,Ma Z,Zhai Y,Lv C,Yuan P,Zhu F,Wei L,Li Q,Qi X
Sat Apr 16 00:00:00 UTC 2022
Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis.
Cell metabolism
Puchalska P,Martin SE,Huang X,Lengfeld JE,Daniel B,Graham MJ,Han X,Nagy L,Patti GJ,Crawford PA
Tue Feb 05 00:00:00 UTC 2019
Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis.
Cell metabolism
Puchalska P,Martin SE,Huang X,Lengfeld JE,Daniel B,Graham MJ,Han X,Nagy L,Patti GJ,Crawford PA
Tue Feb 05 00:00:00 UTC 2019
Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis.
Cell metabolism
Puchalska P,Martin SE,Huang X,Lengfeld JE,Daniel B,Graham MJ,Han X,Nagy L,Patti GJ,Crawford PA
Tue Feb 05 00:00:00 UTC 2019
Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis.
Cell metabolism
Puchalska P,Martin SE,Huang X,Lengfeld JE,Daniel B,Graham MJ,Han X,Nagy L,Patti GJ,Crawford PA
Tue Feb 05 00:00:00 UTC 2019
Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.
Oncogene
Nishimura T,Nakata A,Chen X,Nishi K,Meguro-Horike M,Sasaki S,Kita K,Horike SI,Saitoh K,Kato K,Igarashi K,Murayama T,Kohno S,Takahashi C,Mukaida N,Yano S,Soga T,Tojo A,Gotoh N
Mon Apr 01 00:00:00 UTC 2019
Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.
Oncogene
Nishimura T,Nakata A,Chen X,Nishi K,Meguro-Horike M,Sasaki S,Kita K,Horike SI,Saitoh K,Kato K,Igarashi K,Murayama T,Kohno S,Takahashi C,Mukaida N,Yano S,Soga T,Tojo A,Gotoh N
Mon Apr 01 00:00:00 UTC 2019
Role and therapeutic potential of dietary ketone bodies in lymph vessel growth.
Nature metabolism
García-Caballero M,Zecchin A,Souffreau J,Truong AK,Teuwen LA,Vermaelen W,Martín-Pérez R,de Zeeuw P,Bouché A,Vinckier S,Cornelissen I,Eelen G,Ghesquière B,Mazzone M,Dewerchin M,Carmeliet P
Mon Jul 01 00:00:00 UTC 2019
Ketogenic diet activates protective γδ T cell responses against influenza virus infection.
Science immunology
Goldberg EL,Molony RD,Kudo E,Sidorov S,Kong Y,Dixit VD,Iwasaki A
Fri Nov 15 00:00:00 UTC 2019
Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease.
Acta neuropathologica
Stumpf SK,Berghoff SA,Trevisiol A,Spieth L,Düking T,Schneider LV,Schlaphoff L,Dreha-Kulaczewski S,Bley A,Burfeind D,Kusch K,Mitkovski M,Ruhwedel T,Guder P,Röhse H,Denecke J,Gärtner J,Möbius W,Nave KA,Saher G
Mon Jul 01 00:00:00 UTC 2019
Role of OXCT1 in ovine adipose and preadipocyte differentiation.
Biochemical and biophysical research communications
Zeng J,Zhou SW,Zhao J,Jin MH,Kang DJ,Yang YX,Wang XL,Chen YL
Tue May 14 00:00:00 UTC 2019
Low ketolytic enzyme levels in tumors predict ketogenic diet responses in cancer cell lines in vitro and in vivo.
Journal of lipid research
Zhang J,Jia PP,Liu QL,Cong MH,Gao Y,Shi HP,Yu WN,Miao MY
Sun Apr 01 00:00:00 UTC 2018
Low ketolytic enzyme levels in tumors predict ketogenic diet responses in cancer cell lines in vitro and in vivo.
Journal of lipid research
Zhang J,Jia PP,Liu QL,Cong MH,Gao Y,Shi HP,Yu WN,Miao MY
Sun Apr 01 00:00:00 UTC 2018
Low ketolytic enzyme levels in tumors predict ketogenic diet responses in cancer cell lines in vitro and in vivo.
Journal of lipid research
Zhang J,Jia PP,Liu QL,Cong MH,Gao Y,Shi HP,Yu WN,Miao MY
Sun Apr 01 00:00:00 UTC 2018
Low ketolytic enzyme levels in tumors predict ketogenic diet responses in cancer cell lines in vitro and in vivo.
Journal of lipid research
Zhang J,Jia PP,Liu QL,Cong MH,Gao Y,Shi HP,Yu WN,Miao MY
Sun Apr 01 00:00:00 UTC 2018
CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs.
The Journal of cell biology
Schatton D,Pla-Martin D,Marx MC,Hansen H,Mourier A,Nemazanyy I,Pessia A,Zentis P,Corona T,Kondylis V,Barth E,Schauss AC,Velagapudi V,Rugarli EI
Mon Mar 06 00:00:00 UTC 2017
CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs.
The Journal of cell biology
Schatton D,Pla-Martin D,Marx MC,Hansen H,Mourier A,Nemazanyy I,Pessia A,Zentis P,Corona T,Kondylis V,Barth E,Schauss AC,Velagapudi V,Rugarli EI
Mon Mar 06 00:00:00 UTC 2017
E2F6 Impairs Glycolysis and Activates BDH1 Expression Prior to Dilated Cardiomyopathy.
PloS one
Major JL,Dewan A,Salih M,Leddy JJ,Tuana BS
Tue Aug 08 00:00:00 UTC 2017
E2F6 Impairs Glycolysis and Activates BDH1 Expression Prior to Dilated Cardiomyopathy.
PloS one
Major JL,Dewan A,Salih M,Leddy JJ,Tuana BS
Tue Aug 08 00:00:00 UTC 2017
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress.
Cell research
Huang D,Li T,Wang L,Zhang L,Yan R,Li K,Xing S,Wu G,Hu L,Jia W,Lin SC,Dang CV,Song L,Gao P,Zhang H
Sat Oct 01 00:00:00 UTC 2016
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress.
Cell research
Huang D,Li T,Wang L,Zhang L,Yan R,Li K,Xing S,Wu G,Hu L,Jia W,Lin SC,Dang CV,Song L,Gao P,Zhang H
Sat Oct 01 00:00:00 UTC 2016
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
Nature medicine
Youm YH,Nguyen KY,Grant RW,Goldberg EL,Bodogai M,Kim D,D'Agostino D,Planavsky N,Lupfer C,Kanneganti TD,Kang S,Horvath TL,Fahmy TM,Crawford PA,Biragyn A,Alnemri E,Dixit VD
Sun Mar 01 00:00:00 UTC 2015
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
Nature medicine
Youm YH,Nguyen KY,Grant RW,Goldberg EL,Bodogai M,Kim D,D'Agostino D,Planavsky N,Lupfer C,Kanneganti TD,Kang S,Horvath TL,Fahmy TM,Crawford PA,Biragyn A,Alnemri E,Dixit VD
Sun Mar 01 00:00:00 UTC 2015
Successful adaptation to ketosis by mice with tissue-specific deficiency of ketone body oxidation.
American journal of physiology. Endocrinology and metabolism
Cotter DG,Schugar RC,Wentz AE,d'Avignon DA,Crawford PA
Fri Feb 15 00:00:00 UTC 2013
Successful adaptation to ketosis by mice with tissue-specific deficiency of ketone body oxidation.
American journal of physiology. Endocrinology and metabolism
Cotter DG,Schugar RC,Wentz AE,d'Avignon DA,Crawford PA
Fri Feb 15 00:00:00 UTC 2013
Impact of peripheral ketolytic deficiency on hepatic ketogenesis and gluconeogenesis during the transition to birth.
The Journal of biological chemistry
Cotter DG,Ercal B,d'Avignon DA,Dietzen DJ,Crawford PA
Fri Jul 05 00:00:00 UTC 2013
Impact of peripheral ketolytic deficiency on hepatic ketogenesis and gluconeogenesis during the transition to birth.
The Journal of biological chemistry
Cotter DG,Ercal B,d'Avignon DA,Dietzen DJ,Crawford PA
Fri Jul 05 00:00:00 UTC 2013
Obligate role for ketone body oxidation in neonatal metabolic homeostasis.
The Journal of biological chemistry
Cotter DG,d'Avignon DA,Wentz AE,Weber ML,Crawford PA
Fri Mar 04 00:00:00 UTC 2011
Obligate role for ketone body oxidation in neonatal metabolic homeostasis.
The Journal of biological chemistry
Cotter DG,d'Avignon DA,Wentz AE,Weber ML,Crawford PA
Fri Mar 04 00:00:00 UTC 2011
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy.
BMC cancer
Maurer GD,Brucker DP,Bähr O,Harter PN,Hattingen E,Walenta S,Mueller-Klieser W,Steinbach JP,Rieger J
Tue Jul 26 00:00:00 UTC 2011
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy.
BMC cancer
Maurer GD,Brucker DP,Bähr O,Harter PN,Hattingen E,Walenta S,Mueller-Klieser W,Steinbach JP,Rieger J
Tue Jul 26 00:00:00 UTC 2011
Adaptation of myocardial substrate metabolism to a ketogenic nutrient environment.
The Journal of biological chemistry
Wentz AE,d'Avignon DA,Weber ML,Cotter DG,Doherty JM,Kerns R,Nagarajan R,Reddy N,Sambandam N,Crawford PA
Fri Aug 06 00:00:00 UTC 2010
Adaptation of myocardial substrate metabolism to a ketogenic nutrient environment.
The Journal of biological chemistry
Wentz AE,d'Avignon DA,Weber ML,Cotter DG,Doherty JM,Kerns R,Nagarajan R,Reddy N,Sambandam N,Crawford PA
Fri Aug 06 00:00:00 UTC 2010
Adaptation of myocardial substrate metabolism to a ketogenic nutrient environment.
The Journal of biological chemistry
Wentz AE,d'Avignon DA,Weber ML,Cotter DG,Doherty JM,Kerns R,Nagarajan R,Reddy N,Sambandam N,Crawford PA
Fri Aug 06 00:00:00 UTC 2010
Adaptation of myocardial substrate metabolism to a ketogenic nutrient environment.
The Journal of biological chemistry
Wentz AE,d'Avignon DA,Weber ML,Cotter DG,Doherty JM,Kerns R,Nagarajan R,Reddy N,Sambandam N,Crawford PA
Fri Aug 06 00:00:00 UTC 2010
