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Invitrogen
OXCT1 Polyclonal Antibody
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FIGURE: 1 / 6
OXCT1 Antibody (PA5-100002) in ICC/IF
Immunofluorescent analysis of OXCT1 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and OXCT1 polyclonal antibody (Product # PA5-100002) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-100002
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human OXCT1(Accession P55809), corresponding to amino acid residues A147-F197.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2815532
Product Specific Information
Antibody detects endogenous levels of total OXCT1.
Target Information
This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-oxoacid CoA transferase 1; 3-oxoacid CoA-transferase 1; 3-oxoacid-CoA transferase 1; oxct1 {ECO:0000312|EMBL:AAI66478.1}; SCOT; SCOT-s; somatic-type succinyl CoA:3-oxoacid CoA-transferase; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; somatic-type succinyl-CoA:3-oxoacid-CoA-transferase; succinyl CoA:3-oxoacid CoA transferase; succinyl-CoA:3-ketoacid CoA transferase; Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; succinyl-CoA:3-ketoacid-CoA transferase; succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial; Succinyl-CoA:3-oxoacid CoA transferase
Gene Aliases: 2610008O03Rik; OXCT; OXCT1; Oxct2a; SCOT; Scot-s
UniProt ID: (Human) P55809, (Mouse) Q9CV92, (Rat) B2GV06
Entrez Gene ID: (Human) 5019, (Mouse) 67041, (Rat) 690163
brain development
heart development
response to nutrient
response to hormone
response to activity
positive regulation of insulin secretion involved in cellular response to glucose stimulus
ketone catabolic process
response to drug
response to starvation
response to ethanol
cellular ketone body metabolic process
ketone body catabolic process
adipose tissue development
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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