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Abnova
OXER1 Polyclonal Antibody, MaxPab™
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Product Details
H00165140-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
OXER1 (NP_683765.1, 1 a.a. approximately 423 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLCHRGGQLI VPIIPLCPEH SCRGRRLQNL LSGPWPKQPM ELHNLSSPSP SLSSSVLPPS FSPSPSSAPS AFTTVGGSSG GPCHPTSSSL VSAFLAPILA LEFVLGLVGN SLALFIFCIH TRPWTSNTVF LVSLVAADFL LISNLPLRVD YYLLHETWRF GAAACKVNLF MLSTNRTASV VFLTAIALNR YLKVVQPHHV LSRASVGAAA RVAGGLWVGI LLLNGHLLLS TFSGPSCLSY RVGTKPSASL RWHQALYLLE FFLPLALILF AIVSIGLTIR NRGLGGQAGP QRAMRVLAMV VAVYTICFLP SIIFGMASMV AFWLSACRSL DLCTQLFHGS LAFTYLNSVL DPVLYCFSSP NFLHQSRALL GLTRGRQGPV SDESSYQPSR QWRYREASRK AEAIGKLKVQ GEVSLEKEGS SQG
Target Information
TG1019 is a G protein-coupled receptor that functions as a chemoattractant for eosinophils and neutrophils. TG1019 is expressed in various tissues except the brain, with the highest expression in liver, kidney, peripheral leukocyte, lung and spleen. TG1019 interacts with the protein OXE to form TG1019/OXE, a Galpha i/o protein-coupled receptor. Signals from TG1019 are transduced via a Galpha i/o protein to PLC/calcium, MEK/ERK and PI3K/Akt pathways. Signal transduction from TG1019 following stimulation with 5-oxo-6E,8Z,11Z,14Z eicosatetraenoic acid (5-oxo-ETE) induces intracellular calcium mobilization and rapid activation of MEK/ERK and PI3K/Akt pathways. TG1019 also may play a role in downregulating cAMP production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5-oxo-ETE acid G-protein-coupled receptor 1; 5-oxo-ETE G-protein coupled receptor; G-protein coupled receptor 170; G-protein coupled receptor R527; G-protein coupled receptor TG1019; HEOAD54; OXE receptor; oxoeicosanoid (OXE) receptor 1; Oxoeicosanoid receptor 1
Gene Aliases: GPCR; GPR170; OXER1; TG1019
UniProt ID: (Human) Q8TDS5
Entrez Gene ID: (Human) 165140
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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