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Proteintech
OXSR1 Polyclonal Antibody
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Product Details
15611-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
OXSR1 Fusion Protein Ag8002 (1-308 aa encoded by BC008726)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSEDSSALP WSINRDDYEL QEVIGSGATA VVQAAYCAPK KEKVAIKRIN LEKCQTSMDE LLKEIQAMSQ CHHPNIVSYY TSFVVKDELW LVMKLLSGGS VLDIIKHIVA KGEHKSGVLD ESTIATILRE VLEGLEYLHK NGQIHRDVKA GNILLGEDGS VQIADFGVSA FLATGGDITR NKVRKTFVGT PCWMAPEVME QVRGYDFKAD IWSFGITAIE LATGAAPYHK YPPMKVLMLT LQNDPPSLET GVQDKEMLKK YGKSFRKMIS LCLQKDPEKR PTAAELLRHK FFQKAKNKEF LQEKTLQRA (1-308 aa encoded by BC008726 )
Target Information
OXSR1 serine/threonine kinase or (OSR1) is activated by osmotic stresses and regulates downstream protein kinases such as PAK1 in order to establish the sensor/signaling modules that initiate the cellular response to environmental stress. OXSR1 can be phosphorylated by ATM or ATR during the DNA damage process. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C6orf182; CEP57R; OTTHUMP00000209062; Oxidative stress-responsive 1 protein; oxidative-stress responsive 1; OXSR1; Serine/threonine-protein kinase OSR1
Gene Aliases: 2210022N24Rik; 2810422B09Rik; AI462649; AW209236; KIAA1101; mKIAA1101; OSR1; OXSR1
UniProt ID: (Human) O95747, (Mouse) Q6P9R2
Entrez Gene ID: (Human) 9943, (Mouse) 108737, (Rat) 316064
magnesium ion binding
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding
protein phosphorylation
response to oxidative stress
regulation of mitotic cell cycle
phosphorylation
peptidyl-threonine phosphorylation
signal transduction by protein phosphorylation
stress-activated protein kinase signaling cascade
activation of protein kinase activity
intracellular signal transduction
regulation of apoptotic process
cellular hypotonic response
negative regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transport
negative regulation of rubidium ion transport
negative regulation of rubidium ion transmembrane transporter activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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