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Abnova
OXSR1 Monoclonal Antibody (3A8)
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Product Details
H00009943-M16
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3A8
Immunogen
OXSR1 (AAH08726.1, 1 a.a. approximately 527 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MSEDSSALPW SINRDDYELQ EVIGSGATAV VQAAYCAPKK EKVAIKRINL EKCQTSMDEL LKEIQAMSQC HHPNIVSYYT SFVVKDELWL VMKLLSGGSV LDIIKHIVAK GEHKSGVLDE STIATILREV LEGLEYLHKN GQIHRDVKAG NILLGEDGSV QIADFGVSAF LATGGDITRN KVRKTFVGTP CWMAPEVMEQ VRGYDFKADI WSFGITAIEL ATGAAPYHKY PPMKVLMLTL QNDPPSLETG VQDKEMLKKY GKSFRKMISL CLQKDPEKRP TAAELLRHKF FQKAKNKEFL QEKTLQRAPT ISERAKKVRR VPGSSGRLHK TEDGGWEWSD DEFDEESEEG KAAISQLRSP RVKESISNSE LFPTTDPVGT LLQVPEQISA HLPQPAGQIA TQPTQVSLPP TAEPAKTAQA LSSGSGSQET KIPISLVLRL RNSKKELNDI RFEFTPGRDT AEGVSQELIS AGLVDGRDLV IVAANLQKIV EEPQSNRSVT FKLASGVEGS DIPDDGKLIG FAQLSIS
Target Information
OXSR1 serine/threonine kinase or (OSR1) is activated by osmotic stresses and regulates downstream protein kinases such as PAK1 in order to establish the sensor/signaling modules that initiate the cellular response to environmental stress. OXSR1 can be phosphorylated by ATM or ATR during the DNA damage process. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C6orf182; CEP57R; OTTHUMP00000209062; Oxidative stress-responsive 1 protein; oxidative-stress responsive 1; OXSR1; Serine/threonine-protein kinase OSR1
Gene Aliases: 2210022N24Rik; 2810422B09Rik; AI462649; AW209236; KIAA1101; mKIAA1101; OSR1; OXSR1
UniProt ID: (Human) O95747, (Mouse) Q6P9R2
Entrez Gene ID: (Human) 9943, (Mouse) 108737, (Rat) 316064
magnesium ion binding
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding
protein phosphorylation
response to oxidative stress
regulation of mitotic cell cycle
phosphorylation
peptidyl-threonine phosphorylation
signal transduction by protein phosphorylation
stress-activated protein kinase signaling cascade
activation of protein kinase activity
intracellular signal transduction
regulation of apoptotic process
cellular hypotonic response
negative regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transport
negative regulation of rubidium ion transport
negative regulation of rubidium ion transmembrane transporter activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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