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Invitrogen
Oct-2 Monoclonal Antibody (ZO001)
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FIGURE: 1 / 8
Oct-2 Antibody (39-5400) in WB
Western blot analysis was performed on nuclear enriched extracts (30 µg lysate) of Raji (Lane 1), Ramos (Lane 2), NTERA-2 (Lane 3), MOLT4 (Lane 4), NCCIT (Lane 5), A549 (Lane 6), HeLa (Lane 7), HEK-293 (Lane 8) and Jurkat (Lane 9). The blot was probed with Anti- Oct-2 Mouse Monoclonal Antibody (Product # 39-5400, 1 µg/mL) and detected by chemiluminescence using Goat anti-Mouse IgG (H+L) Superclonal™ Secondary Antibody, HRP conjugate (Product # A28177, 0.25 µg/mL, 1:4000 dilution). A 62 kDa band corresponding to Oct-2 was observed in Raji, ... View More
Product Details
39-5400
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
ZO001
Immunogen
Synthetic peptide derived from the C-terminus of human Oct2.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2533419
Target Information
OCT-2 is a transcription factor belonging to the POU homeo-domain family that binds to the Ig gene octamer sites regulating B cell specific genes. OCT-2 protein expression is not restricted to B cells, although expression levels are much higher in these cells. OCT-2 expression is reported to be significantly greater in germinal center derived lymphomas, although other B cell lymphomas also display high levels of expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: homeobox protein; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Oct-2; Octamer-binding protein 2; Octamer-binding transcription factor 2; OTF-2; POU domain, class 2, transcription factor 2
Gene Aliases: Oct-2; OCT2; OTF2; POU2F2
UniProt ID: (Human) P09086
Entrez Gene ID: (Human) 5452
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein domain specific binding
sequence-specific DNA binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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