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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Melanopsin is an opsin-like protein found in the retinal ganglion cells of mammals. Melanopsin is believed to be part of a secondary optical system that parallels that of the classic rod and cone system. This second system reports directly to the suprachiasmatic nucleus and is responsible for regulation of circadian rhythms. Melanopsin is believed to be the primary photopigment responsible for the regulation of these circadian rhythms, and Melanopsin knockout mice have been generated which demonstrate decreased capacity to entrain to light and dark cycles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: LOC721663; Melanopsin; MGC142118; OPN 4; opn4 {ECO:0000312|RGD:621701}; Opsin-4
Gene Aliases: 1110007J02Rik; Gm533; MOP; Mopn; OPN4
UniProt ID: (Human) Q9UHM6, (Mouse) Q9QXZ9, (Rat) Q8R456
Entrez Gene ID: (Human) 94233, (Mouse) 30044, (Rat) 192223
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