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Invitrogen
Orexin A Polyclonal Antibody
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FIGURE: 1 / 1
Orexin A Antibody (PA5-70436) in WB
Journal of neuroinflammation 2020 -
Fig. 1 Time-course study of OXA, OXR1, and OXR2 using western blot. a Representative protein bands. b Western blot quantitative analyses of OXA, one-way ANOVA, * p < 0.05 vs. sham group. Error bars represent the means +- SD, n = 6 per group. c Western blot quantitative analyses of OXR1, one-way ANOVA, * p < 0.05 vs. sham group. Error bars represent the means +- SD, n = 6 per group. d Western blot qu... View More
Product Details
PA5-70436
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the middle region of rat Orexin A
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2691142
Product Specific Information
This target displays homology in the following species: Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 93%; Mouse: 100%; Pig: 93%; Rabbit: 93%; Rat: 100%; Sheep: 93%
Target Information
This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Hcrt; Hypocretin; Hypocretin (orexin) neuropeptide; Hypocretin neuropeptide precursor; orexin; Orexin precursor; Prepro-orexin; Preprohypocretin
Gene Aliases: Hcrt; orexin-A; Ox; Ppox
UniProt ID: (Rat) O55232
Entrez Gene ID: (Rat) 25723
temperature homeostasis
behavioral fear response
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
feeding behavior
negative regulation of DNA replication
eating behavior
negative regulation of potassium ion transport
regulation of neurotransmitter secretion
release of sequestered calcium ion into cytosol
positive regulation of calcium ion transport
negative regulation of transmission of nerve impulse
positive regulation of transmission of nerve impulse
excitatory postsynaptic potential
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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