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Invitrogen
Osteocalcin Monoclonal Antibody (OC4-30)
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Product Details
MA1-20786
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Dog,
Chicken,
Goat,
Human,
Sheep,
Pig,
Rabbit,
Rat
Published species
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OC4-30
Immunogen
Bovine osteocalcin.
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2064891
Product Specific Information
This antibody does not cross react with mouse Osteocalcin.
Predicted molecular weight of 12 kDa.
Target Information
Osteocalcin belongs to the osteocalcin/matrix Gla-protein family and constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BGP; bone gamma-carboxyglutamate (gla) protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); bone gamma-carboxyglutamate (gla) protein-like; bone gamma-carboxyglutamate protein 2; bone gamma-carboxyglutamate protein osteocalcin; bone gamma-carboxyglutamate; BGLAP; bone gamma-carboxyglutamic acid (Gla) protein (osteocalcin); Bone Gla protein; bone Gla-protein; gamma-carbooxyglutamate (gla) protein; Gamma-carboxyglutamic acid-containing protein; Osteocalcin; PMF1; RP11-54H19.5
Gene Aliases: BGLAP; Bglap2; BGP; Bgpr; Bgpra; BOS_2768; GLA; OC; OCN
UniProt ID: (Human) P02818, (Bovine) P02820, (Rat) P04640
Entrez Gene ID: (Dog) 403762, (Chicken) 396348, (Sheep) 677670, (Human) 632, (Bovine) 281646, (Pig) 397530, (Goat) 100861188, (Rat) 25295, (Rabbit) 100340503
regulation of bone mineralization
biomineral tissue development
skeletal system development
osteoblast differentiation
osteoblast development
signal peptide processing
ER to Golgi vesicle-mediated transport
cell adhesion
cell aging
response to mechanical stimulus
response to gravity
response to zinc ion
response to activity
peptidyl-glutamic acid carboxylation
bone mineralization
response to vitamin K
response to vitamin D
response to testosterone
response to hydroxyisoflavone
odontogenesis
response to drug
response to estrogen
regulation of bone resorption
response to ethanol
regulation of osteoclast differentiation
response to glucocorticoid
bone development
cellular response to vitamin D
cellular response to growth factor stimulus
ossification
aging
response to inorganic substance
response to organic cyclic compound
response to nutrient levels
cellular response to BMP stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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