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Invitrogen
P2Y1 Monoclonal Antibody (4G5B7)
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Product Details
MA5-31815
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
4G5B7
Immunogen
Purified recombinant fragment of human P2RY1 expressed in E. coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2787438
Product Specific Information
Amino acid sequence of the immunogen is proprietary. This antibody has been tested in indirect ELISA.
Target Information
P2Y1 is a Purinergic Receptor that causes a change in platelet shape and potentially leads to platelet aggregation by binding ADP, which results in the mobilization of intracellular calcium ions via activation of phospholipase C. This receptor also mediates the release of the relaxing factor nitric oxide and may be involved in the modulation of neuronal signal transmission. P2Y1 has been reported to be expressed in tissues throughout the body, particularly brain. ESTs have been isolated from human embryo, lung, and placenta libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ADP receptor; ATP receptor; P2 purinoceptor subtype Y1; P2Y purinoceptor 1; p2y-1-r; P2Y1; p2y1r; platelet ADP receptor; Purinergic receptor; purinergic receptor P2Y, G-protein coupled, 1; Purinoceptor p2y1; Purinoceptor p2yr1
Gene Aliases: P2RY1; P2Y1
UniProt ID: (Human) P47900
Entrez Gene ID: (Human) 5028
positive regulation of protein phosphorylation
adenosine receptor signaling pathway
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
aging
glial cell migration
response to mechanical stimulus
regulation of receptor activity
negative regulation of norepinephrine secretion
sensory perception of pain
signal transduction involved in regulation of gene expression
platelet activation
positive regulation of inositol trisphosphate biosynthetic process
G-protein coupled purinergic nucleotide receptor signaling pathway
regulation of vasodilation
eating behavior
positive regulation of ion transport
positive regulation of transcription from RNA polymerase II promoter
positive regulation of hormone secretion
negative regulation of binding
positive regulation of penile erection
positive regulation of ERK1 and ERK2 cascade
response to growth factor
cellular response to organic cyclic compound
protein localization to plasma membrane
relaxation of muscle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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