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Invitrogen
P2Y2 Polyclonal Antibody
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FIGURE: 1 / 5
P2Y2 Antibody (PA5-30113) in ICC/IF
Immunocytochemistry analysis of P2Y2 in DIV14 rat E18 primary cortical neurons fixed in 4% paraformaldehyde at RT for 15 min. Samples were incubated with P2Y2 polyclonal antibody (Product # PA5-30113) using a dilution of 1:500 (green). Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody [GT1338] diluted at 1:500. Blue: Fluoroshield with DAPI.
Product Details
PA5-30113
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human P2Y2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.12 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2547587
Product Specific Information
Recommended positive controls: 293T, A431, Jurkat, Raji, mouse brain, rat brain.
Predicted reactivity: Human (99%), Mouse (84%), Rat (85%), Pig (82%), Bovine (81%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP receptor; P2U nucleotide receptor; P2U purinoceptor 1; P2U receptor 1; P2U1; P2Y purinoceptor 2; P2Y-like receptor; P2Y2; Purinergic receptor; purinergic receptor P2Y, G-protein coupled, 2; purinoceptor P2Y2; R12
Gene Aliases: HP2U; P2RU1; P2RY2; P2U; P2U1; P2UR; P2Y2; P2Y2R
UniProt ID: (Human) P41231, (Mouse) P35383
Entrez Gene ID: (Human) 5029, (Mouse) 18442
in utero embryonic development
cellular ion homeostasis
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
aging
positive regulation of neuron projection development
positive regulation of smooth muscle cell migration
sensory perception of pain
negative regulation of ossification
positive regulation of prostaglandin secretion
positive regulation of chemokine production
G-protein coupled purinergic nucleotide receptor signaling pathway
wound healing
regulation of vasodilation
positive regulation of penile erection
positive regulation of mucus secretion
response to growth factor
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to purine-containing compound
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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