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Alomone Labs, LTD
P2Y2 Receptor (extracellular) Polyclonal Antibody
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FIGURE: 1 / 3
P2Y2 Receptor (extracellular) Antibody (APR-102-200UL) in IHC (F)
Expression of P2Y2 in mouse hippocampus - Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-P2Y2 Receptor (extracellular) Antibody (#APR-102), (1:200), followed by goat- Anti-rabbit-AlexaFluor-488. P2RY2 immunoreactivity (green) in the hippocampal dentate gyrus appears in blood vessels (horizontal arrows) and in neurons (vertical arrows). Cell nuclei are stained with DAPI... View More
Product Details
APR-102-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(CD)TINGTWEGDELGYK, corresponding to amino acid residues 11- 24 of rat P2RY2, Extracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
Target Information
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP receptor; P2U nucleotide receptor; P2U purinoceptor 1; P2U receptor 1; P2U1; P2Y ATP receptor 2; P2Y purinoceptor 2; P2Y-like receptor; P2Y2; Purinergic receptor; purinergic receptor P2Y, G-protein coupled, 2; purinoceptor P2Y2; R12
Gene Aliases: HP2U; P2RU1; P2RY2; P2U; P2U1; P2UR; P2Y2; P2Y2R
UniProt ID: (Human) P41231, (Mouse) P35383, (Rat) P41232
Entrez Gene ID: (Human) 5029, (Mouse) 18442, (Rat) 29597
in utero embryonic development
cellular ion homeostasis
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
aging
positive regulation of neuron projection development
positive regulation of smooth muscle cell migration
sensory perception of pain
negative regulation of ossification
positive regulation of prostaglandin secretion
positive regulation of chemokine production
G-protein coupled purinergic nucleotide receptor signaling pathway
wound healing
regulation of vasodilation
positive regulation of penile erection
positive regulation of mucus secretion
response to growth factor
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to purine-containing compound
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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