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ADCYAP1 is adenylate cyclase activating polypeptide 1. Mediated by adenylate cyclase activating polypeptide 1 receptors, this polypeptide stimulates adenylate cyclase and subsequently increases the cAMP level in target cells. Adenylate cyclase activating polypeptide 1 is not only a hypophysiotropic hormone, but also functions as a neurotransmitter and neuromodulator. In addition, it plays a role in paracrine and autocrine regulation of certain types of cells. This gene encodes three different mature peptides, including two isotypes, a shorter form and a longer form.
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Protein Aliases: ADCYAP1; caspase-2 binding protein; HSPC190; marginal zone B and B1 cell-specific protein; Marginal zone B- and B1-cell-specific protein; MEDA-7; Mesenteric estrogen-dependent adipose 7; mesenteric oestrogen-dependent adipose gene- 7; MGC126852; MZB1; OTTHUMP00000162201; pacap 38; pERp1; plasma cell-induced ER protein 1; Plasma cell-induced resident endoplasmic reticulum protein; Plasma cell-induced resident ER protein; Proapoptotic caspase adapter protein; proapoptotic caspase adaptor protein
Gene Aliases: 2010001M09Rik; AV064572; HSPC190; MEDA-7; MEDA7; MZB1; PACAP; pERp1; RGD1310251
UniProt ID: (Human) Q8WU39, (Rat) Q561R0, (Mouse) Q9D8I1
Entrez Gene ID: (Human) 51237, (Rat) 291675, (Mouse) 69816
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