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Invitrogen
PACAP Receptor Polyclonal Antibody
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PACAP Receptor Antibody (PA5-33318) in IHC (P)
Immunohistochemistry analysis of PACAP Receptor in human brain, pituitary. Samples were incubated with PACAP Receptor polyclonal antibody (Product # PA5-33318). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Product Details
PA5-33318
Product Specifications
Species Reactivity
Bovine,
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 18 amino acid peptide from N-terminal extracellular domain of human ADCYAP1R1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550702
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Bovine (100%); Dog, Pig (94%); Mouse, Rat, Elephant, Panda (89%).
Antigen retrieval requires Proteinase K treatment.
Target Information
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Alternative splicing of two exons of this gene generates four major splice variants, but their full-length nature has not been determined. PACAP receptor type 1 expression has been documented in adipose, adrenal, bone, brain, colon, ganglion, heart, lung, ovary, pancreas, placenta, spleen, and uterus. ESTs have been isolated from brain and nerve libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADCYAP1 R1; ADCYAP1R 1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; PAC 1; PAC1 receptor; Pac1 receptors; PACAP R 1; PACAP Receptor; PACAP receptor 1; PACAP type I receptor; PACAP-R-1; PACAP-R1; PACAP/VIP receptors; PACAP1 R; PACAP1 receptor; pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop; Pituitary adenylate cyclase-activating polypeptide type I receptor; pvr1
Gene Aliases: ADCYAP1R1; BOS_4300; PAC1; PAC1R; PACAPR; PACAPRI
UniProt ID: (Human) P41586, (Bovine) Q29627
Entrez Gene ID: (Human) 117, (Bovine) 319095
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
activation of phospholipase C activity
spermatogenesis
positive regulation of calcium ion transport into cytosol
cAMP-mediated signaling
cell differentiation
positive regulation of cAMP biosynthetic process
response to estradiol
multicellular organismal response to stress
response to drug
response to ethanol
development of primary female sexual characteristics
negative regulation of cell death
positive regulation of inositol phosphate biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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