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Proteintech
PACSIN1 Polyclonal Antibody
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Product Details
13219-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PACSIN1 Fusion Protein Ag4102 (243-389 aa encoded by BC040228)
Conjugate
Form
Liquid
Concentration
0.39 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VFLKEVLLD IKRHLNLAEN SSYIHVYREL EQAIRGADAQ EDLRWFRSTS GPGMPMNWPQ FEEWNPDLPH TTTKKEKQPK KAEGVALTNA TGAVESTSQA GDRGSVSSYD RGQPYATEWS DDESGNPFGG SETNGGANPF EDDSKGVR (243-389 aa encoded by BC040228)
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dynamin PRD-interacting protein; Dynamin proline-rich domain-interacting protein; Protein kinase C and casein kinase substrate in neurons protein 1; SdpI; Synaptic, dynamin-associated protein I; syndapin 1; Syndapin I; Syndapin-1; Syndapin-I
Gene Aliases: A830061D09Rik; H74; KIAA1379; mKIAA1379; Pacsin; PACSIN1; SDPI; syndapin
UniProt ID: (Human) Q9BY11, (Mouse) Q61644, (Rat) Q9Z0W5
Entrez Gene ID: (Human) 29993, (Mouse) 23969, (Rat) 29704
endocytosis
cytoskeleton organization
actin filament organization
signal transduction
negative regulation of endocytosis
synaptic vesicle endocytosis
neuron development
neuron projection morphogenesis
protein localization to membrane
establishment of protein localization to plasma membrane
membrane tubulation
positive regulation of dendrite development
regulation of endocytosis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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