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Proteintech
PAH Polyclonal Antibody
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Product Details
16347-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PAH Fusion Protein Ag9541 (177-452 aa encoded by BC026251)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VEYMEEGKK TWGTVFKTLK SLYKTHACYE YNHIFPLLEK YCGFHEDNIP QLEDVSQFLQ TCTGFRLRPV AGLLSSRDFL GGLAFRVFHC TQYIRHGSKP MYTPEPDICH ELLGHVPLFS DRSFAQFSQE IGLASLGAPD EYIEKLATIY WFTVEFGLCK QGDSIKAYGA GLLSSFGELQ YCLSEKPKLL PLELEKTAIQ NYTVTEFQPL YYVAESFNDA KEKVRNFAAT IPRPFSVRYD PYTQRIEVLD NTQQLKILAD SINSEIGILC SALQKIK (177-452 aa encoded by BC026251 )
Target Information
PAH encodes the enzyme phenylalanine hydroxylase that is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: PAH; Phe-4-monooxygenase; phenylalanine 4-monooxygenase; Phenylalanine-4-hydroxylase
Gene Aliases: AW106920; PAH; PH; PKU; PKU1
UniProt ID: (Human) P00439, (Mouse) P16331
Entrez Gene ID: (Human) 5053, (Mouse) 18478, (Rat) 24616
phenylalanine 4-monooxygenase activity
iron ion binding
amino acid binding
protein homodimerization activity
cofactor binding
catalytic activity
monooxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
metal ion binding
L-phenylalanine catabolic process
tyrosine biosynthetic process
cellular amino acid biosynthetic process
protein hydroxylation
neurotransmitter biosynthetic process
catecholamine biosynthetic process
tetrahydrobiopterin metabolic process
oxidation-reduction process
L-phenylalanine metabolic process
metabolic process
aromatic amino acid family metabolic process
pteridine-containing compound metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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