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Immunogen sequence: SNMANTSPSV KSKEDQGLSG HDEKENPFA
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 79%.
Most mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein (PABP; see MIM 604679) enhances translation by circularizing mRNA through its interaction with the translation initiation factor EIF4G1 (MIM 600495) and the poly(A) tail. Various PABP-binding proteins regulate PABP activity, including PAIP1 (MIM 605184), a translational stimulator, and PAIP2A (MIM 605604) and PAIP2B, translational inhibitors (Derry et al., 2006 [PubMed 17381337]).[supplied by OMIM, Mar 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PABP-interacting protein 2B; PAIP-2B; poly(A)-binding protein-interacting protein 2B; Polyadenylate-binding protein-interacting protein 2B
Gene Aliases: KIAA1155; PAIP2B
UniProt ID: (Human) Q9ULR5
Entrez Gene ID: (Human) 400961
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