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Proteintech
PANK1/2/3 Polyclonal Antibody
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Product Details
12466-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PANK1/2/3 Fusion Protein Ag3140 (61-370 aa encoded by BC013705)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TGIRDVHLE LKDLTLFGRR GNLHFIRFPT QDLPTFIQMG RDKNFSTLQT VLCATGGGAY KFEKDFRTIG NLHLHKLDEL DCLVKGLLYI DSVSFNGQAE CYYFANASEP ERCQKMPFNL DDPYPLLVVN IGSGVSILAV HSKDNYKRVT GTSLGGGTFL GLCSLLTGCE SFEEALEMAS KGDSTQADKL VRDIYGGDYE RFGLPGWAVA SSFGNMIYKE KRESVSKEDL ARATLVTITN NIGSVARMCA VNEKINRVVF VGNFLRVNTL SMKLLAYALD YWSKGQLKAL FLEHEGYFGA VGALLGLPNF S (61-370 aa encoded by BC013705)
Target Information
This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Hallervorden-Spatz syndrome; hPanK; hPanK2; hPanK3; mPank; mPanK3; Pantothenate kinase 1; pantothenate kinase 2 (Hallervorden-Spatz syndrome); Pantothenate kinase 2, mitochondrial; Pantothenate kinase 3; Pantothenic acid kinase 1; Pantothenic acid kinase 2; Pantothenic acid kinase 3
Gene Aliases: 4933409I19Rik; AI642621; C20orf48; HARP; HSS; NBIA1; PANK; PANK1; Pank1b; PANK2; PANK3; PKAN
UniProt ID: (Human) Q8TE04, (Human) Q9BZ23, (Human) Q9H999, (Mouse) Q8K4K6, (Mouse) Q7M753, (Mouse) Q8R2W9
Entrez Gene ID: (Human) 53354, (Human) 80025, (Human) 79646, (Mouse) 75735, (Rat) 294088, (Rat) 296167, (Mouse) 74450, (Mouse) 211347, (Rat) 360511
coenzyme biosynthetic process
coenzyme A biosynthetic process
phosphorylation
spermatid development
aerobic respiration
regulation of mitochondrial membrane potential
mitochondrion morphogenesis
pantothenate metabolic process
regulation of fatty acid metabolic process
regulation of triglyceride metabolic process
regulation of bile acid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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