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This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver.
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Protein Aliases: hPanK3; mPanK3; Pantothenate kinase 3; Pantothenic acid kinase 3
Gene Aliases: PANK3
UniProt ID: (Human) Q9H999, (Mouse) Q8R2W9
Entrez Gene ID: (Human) 79646, (Mouse) 211347, (Rat) 360511
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